Evidence map›Paper›PMID 39684388›Full record

ArticleInternational journal of molecular sciences2024

Indian Medicinal Plant-Derived Phytochemicals as Potential Antidotes for Snakebite: A Pharmacoinformatic Study of Atrolysin Inhibitors.

Deva Asirvatham Ravi, Du Hyeon Hwang, Ramachandran Loganathan Mohan Prakash, Changkeun Kang, Euikyung Kim

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deva Asirvatham RaviCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Du Hyeon HwangCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Ramachandran Loganathan Mohan PrakashCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Changkeun KangCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-5114-5096
Euikyung KimCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0003-3356-3072

Funding

Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (RS-2023-00276023 and NRF-2021R1I1A306005711)
6 · The paper itself

Abstract

Snakebite envenoming is a significant health threat, particularly in tropical regions, causing substantial morbidity and mortality. Traditional treatments, including antivenom therapy, have limitations and associated risks. This research aims to discover novel phytochemical antidotes for snakebites, specifically targeting the western diamondback rattlesnake (

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationPhytochemicalsPlants, MedicinalSnake BitesAnimalsAntidotesAntiveninsBinding SitesCrotalid VenomsCrotalusHumansIndiaMetalloproteasesAntidotesAntiveninsCrotalid VenomsMetalloproteasesPhytochemicalsAtrolysindensity functional theory (DFT)metalloproteinaseMMPBSAmolecular dynamicssnake venom

Identifiers

PMID39684388
PMCPMC11641534

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.