Evidence map›Paper›PMID 39684309›Full record

ArticleInternational journal of molecular sciences2024

Transcriptional Regulation of the Human MGP Promoter: Identification of Downstream Repressors.

Helena Caiado, M Leonor Cancela, Natércia Conceição

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helena CaiadoCenter of Marine Sciences (CCMAR), University of Algarve, 8005-139 Faro, Portugal.
M Leonor CancelaCenter of Marine Sciences (CCMAR), University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0003-3114-6662
Natércia ConceiçãoCenter of Marine Sciences (CCMAR), University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-5057-0912

Funding

Fundação para a Ciência e Tecnologia PD/BD/128341/2017 and COVID/BD/152110/2021Fundação para a Ciência e Tecnologia UIDB/04326/2020, UIDP/04326/2020 and LA/P/0101/2020
6 · The paper itself

Abstract

Matrix Gla protein (MGP) is a vitamin K-dependent γ-carboxylated protein that was initially identified as a physiological inhibitor of ectopic calcification, primarily affecting cartilage and the vascular system. Mutations in the

Indexed as

Calcium-Binding ProteinsExtracellular Matrix ProteinsGATA1 Transcription FactorMatrix Gla ProteinPromoter Regions, GeneticYY1 Transcription FactorBinding SitesCCAAT-Enhancer-Binding ProteinsCell Line, TumorCore Binding Factor Alpha 1 SubunitCpG IslandsGene Expression RegulationGene Expression Regulation, NeoplasticHumansNeoplasmsTranscription, GeneticCalcium-Binding ProteinsCCAAT-Enhancer-Binding ProteinsCore Binding Factor Alpha 1 SubunitExtracellular Matrix ProteinsGATA1 protein, humanGATA1 Transcription FactorMatrix Gla ProteinRUNX2 protein, humanYY1 protein, humanYY1 Transcription FactorC/EBPαGATA1methylationMGPtranscriptional regulationYY1

Identifiers

PMID39684309
PMCPMC11641715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.