Evidence map›Paper›PMID 39684278›Full record

ArticleInternational journal of molecular sciences2024

The Oncogenic Role of

Sawarot Srisathaporn, Chamsai Pientong, Chukkris Heawchaiyaphum, Thawaree Nukpook, Sirinart Aromseree, Tipaya Ekalaksananan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sawarot SrisathapornDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Chamsai PientongDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-2797-043X
Chukkris HeawchaiyaphumDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Thawaree NukpookDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Sirinart AromsereeDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-4320-1166
Tipaya EkalaksanananDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-2406-2356

Funding

Faculty of Medicine, Khon Kaen University, Thailand IN64213Research and Graduate Studies, Khon Kaen University RP67-1-001Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program PHD/0200/2560
6 · The paper itself

Abstract

Dysregulated long non-coding RNA (lncRNA) expression is linked to various cancers and may be influenced by oncogenic Epstein-Barr virus (EBV) infection, a known and detectable risk factor in oral squamous cell carcinoma (OSCC) patients. However, research on the oncogenic role of EBV-induced lncRNAs in OSCC is limited. To identify lncRNA-associated EBV infection and OSCC carcinogenesis, the differential expression of RNA-seq datasets from paired normal adjacent and OSCC tissues, and microarray data from EBV-negative and EBV-positive SCC25 cells, were identified and selected, respectively, for interaction, functional analysis, and CCK-8 cell proliferation, wound healing, and invasion Transwell assays. In OSCC tissues, 6731 differentially expressed lncRNAs were identified when compared to normal tissues from RNA-seq datasets, with 295 linked to EBV-induced OSCC carcinogenesis from microarray datasets. The EBV-induced lncRNA

Indexed as

Carcinoma, Squamous CellEpstein-Barr Virus InfectionsGene Expression Regulation, NeoplasticHerpesvirus 4, HumanMouth NeoplasmsRNA, Long NoncodingCarcinogenesisCell Line, TumorCell MovementCell ProliferationGene Expression ProfilingHumansTranscriptomeRNA, Long NoncodingEpstein–Barr viruslong non-coding RNAoral squamous cell carcinomaVWA8-AS1

Identifiers

PMID39684278
PMCPMC11641457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.