Evidence map›Paper›PMID 39684141›Full record

ArticlePolymers2024

Encapsulation of Thymol in Ethyl Cellulose-Based Microspheres and Evaluation of Its Sustained Release for Food Applications.

Iro Giotopoulou, Haralambos Stamatis, Nektaria-Marianthi Barkoula

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iro GiotopoulouDepartment of Materials Science and Engineering, University of Ioannina, GR-45110 Ioannina, Greece.
Haralambos StamatisDepartment of Biological Applications and Technology, University of Ioannina, GR-45110 Ioannina, Greece.ORCID 0000-0002-8196-4885
Nektaria-Marianthi BarkoulaDepartment of Materials Science and Engineering, University of Ioannina, GR-45110 Ioannina, Greece.ORCID 0000-0003-0917-3920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food waste is a global concern with enormous economic, environmental and social impacts that has contributed to active packaging evolution. However, incorporating bioactive substances into the packaging can deteriorate its physicochemical and mechanical characteristics. Thus, the objective of this work was to entrap the natural bioactive compound thymol into microparticles and apply them in the form of pads for the controlled release of bioactivity in food packaging material. The physicochemical characteristics and bioactivity of five different ethyl cellulose-based microparticles were evaluated. Increasing the amount of thymol in the formulation led to higher encapsulation efficiency. Encapsulation resulted in a substantial increase of >10-20 °C in the volatilization temperature of thymol, and the release of thymol occurred following a sustained profile, best described by the Higuchi release kinetic model. Increasing the polymer to thymol ratio in the microparticles resulted in higher thermal stability and a more gradual release profile. While all formulations demonstrated considerable inhibition of

Indexed as

active packagingentrapmentethyl cellulosemicroparticlesmicrospheresthymol

Identifiers

PMID39684141
PMCPMC11644189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.