Evidence map›Paper›PMID 39683933›Full record

ArticleMolecules (Basel, Switzerland)2024

Invisible but Insidious Effects of Microplastics.

Natalia A Stefanova, Yulia S Sotnikova, Aleksandra E Osechkova, Elena V Karpova, Dmitriy N Polovyanenko, Anzhella Zh Fursova, Daria A Kiseleva, Tatyana G Tolstikova, Nataliya G Kolosova, Elena G Bagryanskaya

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Overall effects of microplastics on brain.Frontiers in toxicology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Natalia A StefanovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Lavrentjev Avenue 10, 630090 Novosibirsk, Russia.
Yulia S SotnikovaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Aleksandra E OsechkovaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.ORCID 0009-0007-5841-9567
Elena V KarpovaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.ORCID 0000-0001-8803-4237
Dmitriy N PolovyanenkoN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Anzhella Zh FursovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Lavrentjev Avenue 10, 630090 Novosibirsk, Russia.
Daria A KiselevaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.ORCID 0000-0002-3932-2491
Tatyana G TolstikovaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.ORCID 0000-0002-3750-2958
Nataliya G KolosovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Lavrentjev Avenue 10, 630090 Novosibirsk, Russia.ORCID 0000-0003-2398-8544
Elena G BagryanskayaN.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.ORCID 0000-0003-0057-383X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence on the adverse health impacts of microplastics (MPs) is available, but their associated risks to the well-being of humans and long-term impacts are poorly understood. An indicator of the remote effects of MPs may be their influence on the rate of aging. To assess the effects of MPs on the aging process, we used accelerated senescence OXYS rats that develop a complex of geriatric diseases. We prepared the polyethylene terephthalate MPs (2-6 microns in size) and in OXYS and Wistar (maternal strain) rats assessed the influence of chronic administration of MPs (10 or 100 mg/kg per day from age 1.5 to 3.5 months,) on the hematological and biochemical blood parameters, spatial learning, and memory. In addition, the effects of MPs on the development of cataracts and retinopathy, similar to age-related macular degeneration (AMD), in OXYS rats were assessed. We found that in the absence of significant changes in standard clinical blood parameters, chronic MP administration negatively affected the cognitive functions of both Wistar rats and OXYS rats. Additionally, a dose of 100 mg/kg MPs contributed to cataract and AMD progression in OXYS rats. Our results suggest that MPs may increase the rate of aging and, in the long term, lifespan.

Indexed as

CataractMicroplasticsRats, WistarAgingAnimalsFemaleMacular DegenerationMaleMemoryPolyethylene TerephthalatesRatsSpatial LearningMicroplasticsPolyethylene Terephthalatesage-related macular degenerationAlzheimer’s diseasecognitive abilitymemorymicroplasticOXYS ratspolymers

Identifiers

PMID39683933
PMCPMC11643646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.