Evidence map›Paper›PMID 39683849›Full record

ArticleMolecules (Basel, Switzerland)2024

Raspberry Pomace as a Good Additive to Apple Freeze-Dried Fruit Bars: Biological Properties and Sensory Evaluation.

Urszula Szymanowska, Monika Karaś, Anna Jakubczyk, Janusz Kocki, Rafał Szymanowski, Ireneusz Tomasz Kapusta

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Urszula SzymanowskaDepartment of Biochemistry and Food Chemistry, University of Life Sciences, 8 Skromna Str., 20-704 Lublin, Poland.ORCID 0000-0001-9692-2111
Monika KaraśDepartment of Biochemistry and Food Chemistry, University of Life Sciences, 8 Skromna Str., 20-704 Lublin, Poland.ORCID 0000-0002-6082-3864
Anna JakubczykDepartment of Biochemistry and Food Chemistry, University of Life Sciences, 8 Skromna Str., 20-704 Lublin, Poland.ORCID 0000-0002-1087-2000
Janusz KockiDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwiłłowska Str., 20-080 Lublin, Poland.ORCID 0000-0002-9541-6353
Rafał SzymanowskiDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwiłłowska Str., 20-080 Lublin, Poland.ORCID 0009-0004-4650-8704
Ireneusz Tomasz KapustaDepartment Food Technology and Human Nutrition, Institute of Food Technology, College of Natural Science, University of Rzeszów, 4 Zelwerowicza Str., 35-601 Rzeszów, Poland.ORCID 0000-0002-1197-2361

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the impact of adding raspberry pomace to the phenolic content and biological properties of freeze-dried apple/raspberry bars. The bars were prepared by replacing apple puree with raspberry pomace (5-50%), and their phenolic compounds were assessed using ethanol and buffer extracts. This work also explored the potential bioaccessibility of phenolic compounds in enriched bars through a simulated digestion process (digest). Antioxidant, anti-inflammatory (LOX, COX-2 inhibition), antihypertensive (ACE inhibition), and antiproliferative effects on AGS and HT-29 cancer cells were evaluated. The total polyphenol content was highest in the all bar variants post-digestion. The highest-904.26 ± 23.5 mg/100 g-was determined for the B50 sample In the enriched bars, the concentration of chlorogenic acid decreased from 6.99 ± 1.08 mg/L for BP5 to 2.75 ± 0.32 mg/L for BP50, but the ellagic acid concentration increased from 1.46 ± 0.02 mg/L for BP5 to 12.73 ± 0.09 mg/L for BP50. Among the tested extracts, the highest antioxidant and LOX, COX-2 inhibiting activity was determined for digest. The ability to neutralize free radicals increased with raspberry pomace addition from 3.63 ± 0.26 mM TE/100 g for BC to 5.58 ± 0.22 mM TE/100 g for the BP50 sample. ACE inhibition was quite similar for ethanolic and digest extracts, but much weaker for buffer extracts. The lowest EC50 value was 1.04 ± 0.03 mg/mL for the BP30 ethanolic sample. Analyzed extracts showed antiproliferative activity against both tested cell lines. The EC50 values for HT-29 cancer cells decreased from 0.354 ± 0.031 mg/mL for BC to 0.026 ± 0.006 mg/mL for the BP50 digest sample. It can be assumed that the BP30 bar best met the assumed criteria, and is optimal for both sensory quality (receiving an average score of 4.45) and health benefits.

Indexed as

AntioxidantsFreeze DryingFruitMalusPlant ExtractsRubusAnti-Inflammatory AgentsCell Line, TumorCell ProliferationHT29 CellsHumansPhenolsPolyphenolsAnti-Inflammatory AgentsAntioxidantsPhenolsPlant ExtractsPolyphenolsantihypertensiveanti-inflammatoryantioxidantantiproliferativefreeze-dried apple/raspberry barspomacepotential bioaccessibility

Identifiers

PMID39683849
PMCPMC11643381

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.