Evidence map›Paper›PMID 39683795›Full record

ArticleMolecules (Basel, Switzerland)2024

Antiprotozoal Activity Against

Ulises Murrieta-Dionicio, Fernando Calzada, Elizabeth Barbosa, Miguel Valdés, Benito Reyes-Trejo, Holber Zuleta-Prada, Diana Guerra-Ramírez, Federico Del Río-Portilla

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bioassay-Guided Fractionation ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Advances in pharmacological and pharmaceutical sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ulises Murrieta-DionicioLaboratorio de Productos Naturales, Área de Química, Departamento de Preparatoria Agrícola, Universidad Autónoma Chapingo, km 38.5 Carretera México-Texcoco, Chapingo 56230, Mexico.ORCID 0000-0003-1041-4090
Fernando CalzadaUnidad de Investigación Médica en Farmacología, UMAE Hospital de Especialidades, 2° Piso CORSE Centro Médico Nacional Siglo XXI, IMSS, Av. Cuauhtémoc 330, Col. Doctores, Ciudad de México 06725, Mexico.ORCID 0000-0003-1851-5988
Elizabeth BarbosaEscuela Superior de Medicina, Instituto Politécnico Nacional, Salvador Díaz Mirón esq. Plan de San Luis S/N, Miguel Hidalgo, Casco de Santo Tomas, Ciudad de México 11340, Mexico.ORCID 0000-0002-7111-7922
Miguel ValdésUnidad de Investigación Médica en Farmacología, UMAE Hospital de Especialidades, 2° Piso CORSE Centro Médico Nacional Siglo XXI, IMSS, Av. Cuauhtémoc 330, Col. Doctores, Ciudad de México 06725, Mexico.ORCID 0000-0001-7401-303X
Benito Reyes-TrejoLaboratorio de Productos Naturales, Área de Química, Departamento de Preparatoria Agrícola, Universidad Autónoma Chapingo, km 38.5 Carretera México-Texcoco, Chapingo 56230, Mexico.
Holber Zuleta-PradaLaboratorio de Productos Naturales, Área de Química, Departamento de Preparatoria Agrícola, Universidad Autónoma Chapingo, km 38.5 Carretera México-Texcoco, Chapingo 56230, Mexico.ORCID 0000-0001-6372-2885
Diana Guerra-RamírezLaboratorio de Productos Naturales, Área de Química, Departamento de Preparatoria Agrícola, Universidad Autónoma Chapingo, km 38.5 Carretera México-Texcoco, Chapingo 56230, Mexico.
Federico Del Río-PortillaInstituto de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diseases caused by intestinal parasites such as protozoa represent a worldwide problem mainly for developing countries. From morbidity in different groups of people to cases of mortality in children and/or immunocompromised patients. In addition to the above, there is growing resistance to the drugs used in the treatment of these diseases, as well as undesirable side effects in patients. Therefore, there is an interest in the search for new alternatives for the base and/or development of new drugs with antiparasitic activities without harmful effects. In this sense, natural products offer to be a diverse source of compounds with biological activities. In this work, we describe the isolation and elucidation by 1D and 2D NMR spectroscopy of three cyclopeptides obtained from seeds of

Indexed as

AnnonaAntiprotozoal AgentsGiardia lambliaMolecular Docking SimulationPeptides, CyclicEntamoeba histolyticaHumansPlant ExtractsAntiprotozoal AgentsPeptides, CyclicPlant Extractsantiprotozoal activitycherimolacyclopeptide DcyclopeptidesEntamoeba hystoliticaGiardia lambliamolecular dockingNMRsquamines C and D

Identifiers

PMID39683795
PMCPMC11643917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.