Evaluation of Quinazolin-2,4-Dione Derivatives as Promising Antibacterial Agents: Synthesis, In Vitro, In Silico ADMET and Molecular Docking Approaches.

Aboubakr H Abdelmonsef, Mohamed El-Naggar, Amal O A Ibrahim, Asmaa S Abdelgeliel, Ihsan A Shehadi, Ahmed M Mosallam, Ahmed Khodairy

Abstract read

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In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aboubakr H AbdelmonsefDepartment of Chemistry, Faculty of Science, South Valley University, Qena 83523, Egypt.ORCID 0000-0002-4616-0224

Mohamed El-NaggarPure and Applied Chemistry Group, Chemistry Department, College of Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0001-8799-0235

Amal O A IbrahimDepartment of Chemistry, Faculty of Science, South Valley University, Qena 83523, Egypt.ORCID 0000-0002-4679-8615

Asmaa S AbdelgelielDepartment of Botany and Microbiology, Faculty of Science, South Valley University, Qena 83523, Egypt.ORCID 0000-0003-2886-1294

Ihsan A ShehadiPure and Applied Chemistry Group, Chemistry Department, College of Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.

Ahmed M MosallamDepartment of Chemistry, Faculty of Science, South Valley University, Qena 83523, Egypt.

Ahmed KhodairyDepartment of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of new quinazolin-2,4-dione derivatives incorporating amide/eight-membered nitrogen-heterocycles

Indexed as

Anti-Bacterial AgentsMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureQuinazolinonesStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsQuinazolinonesantibacterial assessmentdithiolan-4-oneeight-membered nitrogen-heterocyclesmolecular dockingphenyl-thiazolidin-4-onequinazolin-2,4-dione

Identifiers

PMID39683688

DOI10.3390/molecules29235529

PMCPMC11643521

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.