Evidence map›Paper›PMID 39683678›Full record

ArticleMolecules (Basel, Switzerland)2024

New Conjugates of Vancomycin with Cell-Penetrating Peptides-Synthesis, Antimicrobial Activity, Cytotoxicity, and BBB Permeability Studies.

Jarosław Ruczyński, Katarzyna Prochera, Natalia Kaźmierczak, Katarzyna Kosznik-Kwaśnicka, Lidia Piechowicz, Piotr Mucha, Piotr Rekowski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jarosław RuczyńskiLaboratory of Chemistry of Biologically Active Compounds, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.ORCID 0000-0002-1945-194X
Katarzyna ProcheraLaboratory of Chemistry of Biologically Active Compounds, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.ORCID 0009-0007-5366-1055
Natalia KaźmierczakDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Gdańsk, Dębowa 25, 80-204 Gdańsk, Poland.
Katarzyna Kosznik-KwaśnickaDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Gdańsk, Dębowa 25, 80-204 Gdańsk, Poland.ORCID 0000-0002-5023-1531
Lidia PiechowiczDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Gdańsk, Dębowa 25, 80-204 Gdańsk, Poland.ORCID 0000-0001-9222-7330
Piotr MuchaLaboratory of Chemistry of Biologically Active Compounds, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.ORCID 0000-0002-0269-8620
Piotr RekowskiLaboratory of Chemistry of Biologically Active Compounds, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.ORCID 0000-0001-6994-4833

Funding

Gdańsk Medical University 01-65023, task no. 0005239University of Gdańsk BMN 539-T060-B147-24
6 · The paper itself

Abstract

Vancomycin (Van) is a glycopeptide antibiotic commonly used as a last resort for treating life-threatening infections caused by multidrug-resistant bacterial strains, such as

Indexed as

Anti-Bacterial AgentsBlood-Brain BarrierCell-Penetrating PeptidesMicrobial Sensitivity TestsVancomycinCell LineCell SurvivalHumansPermeabilityAnti-Bacterial AgentsCell-Penetrating PeptidesVancomycinantimicrobial assayantimicrobial peptidescell-penetrating peptidesclick chemistrycytotoxicity assayPAMPA-BBB assayvancomycinVan-CPP conjugates

Identifiers

PMID39683678
PMCPMC11643744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.