Evidence map›Paper›PMID 39683563›Full record

ArticleNutrients2024

Study on the Regulatory Mechanism of Niacin Combined with

Xi Liang, Tianhu Shan, Xiumei Zheng, Zhe Zhang, Yanping Fan, Huaqi Zhang, Lanwei Zhang, Hui Liang

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xi LiangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.ORCID 0009-0009-5376-1456
Tianhu ShanDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Xiumei ZhengDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Zhe ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.
Yanping FanDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Huaqi ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.
Lanwei ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-3459-2975
Hui LiangDepartment of Nutrition and Food Hygiene, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China.ORCID 0000-0002-0675-6963

Funding

Qingdao postdoctoral applied research project QDBSH20230102036Youth Program of the Natural Science Foundation of Shandong province ZR2023QH151
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the effects of niacin combined with

methodsA total of 75 8-week-old male C57BL/6N mice were acclimated for one week and randomly divided into five groups: control group, alcohol model group (AFLD), niacin intervention group (NA),

resultsThe results showed that all intervention groups could effectively reduce the serum lipid levels and inflammatory response of mice induced by alcohol to varying degrees. The immunofluorescence analysis showed that the GPR109A in the liver and intestine of the NF group was significantly enhanced compared with the other groups. Niacin combined with

conclusionsNiacin combined with

Indexed as

Fatty Liver, AlcoholicGastrointestinal MicrobiomeLiverMice, Inbred C57BLNiacinReceptors, G-Protein-CoupledReceptors, NicotinicUp-RegulationAnimalsButyric AcidDisease Models, AnimalFatty Acids, VolatileMaleMiceButyric AcidFatty Acids, VolatileHcar2 protein, mouseNiacinReceptors, G-Protein-CoupledReceptors, Nicotinicalcoholic fatty livergut microbiotalipid metabolismniacinprobiotics

Identifiers

PMID39683563
PMCPMC11644097

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.