Evidence map›Paper›PMID 39683346›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Au Ordered Array Substrate for Rapid Detection and Precise Identification of Etomidate in E-Liquid Through Surface-Enhanced Raman Spectroscopy.

Yan Mo, Xiaoping Zhang, Ke Zou, Wen Xing, Xiayang Hou, Yu Zeng, Yugang Cai, Ruixiang Xu, Hongwen Zhang, Weiping Cai

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan MoIntelligent Policing Key Laboratory of Sichuan Province, Sichuan Police College, Luzhou 646000, China.
Xiaoping ZhangAnhui Xianghe Environmental Testing Co., Ltd., Huaibei 235100, China.
Ke ZouAnhui Xianghe Environmental Testing Co., Ltd., Huaibei 235100, China.
Wen XingAnhui Xianghe Environmental Testing Co., Ltd., Huaibei 235100, China.
Xiayang HouIntelligent Policing Key Laboratory of Sichuan Province, Sichuan Police College, Luzhou 646000, China.
Yu ZengDepartment of Intelligent Manufacturing and Automotive Engineering, Luzhou Vocational & Technical College, Luzhou 646000, China.
Yugang CaiLuzhou Public Security Bureau, Luzhou 646000, China.
Ruixiang XuIntelligent Policing Key Laboratory of Sichuan Province, Sichuan Police College, Luzhou 646000, China.
Hongwen ZhangKey Laboratory of Materials Physics, Anhui Key Laboratory of Nanomaterials and Nanotechnology, Institute of Solid State Physics, HFIPS, Chinese Academy of Sciences, Hefei 230031, China.
Weiping CaiKey Laboratory of Materials Physics, Anhui Key Laboratory of Nanomaterials and Nanotechnology, Institute of Solid State Physics, HFIPS, Chinese Academy of Sciences, Hefei 230031, China.ORCID 0000-0002-4515-6098

Funding

Found of Key Laboratory of Toxic and Harmful Gas Monitoring and Early Warning from Ministry of Emergency Management OF2303HFIPS Director's Fund YZJJ202402-CXIntelligent Policing Key Laboratory of Sichuan Province ZNJW2022ZZMS005Luzhou Science and Technology Plan Project 2021-SYF-40National Natural Science Foundation of China 52271242Natural Science Foundation of Anhui Province 2408085J031Shandong Technological Small and Medium-sized Enterprise Innovation Capacity Enhancement Project 2023TSGC0745, 2023TS1084, and 2024ZJ1065
6 · The paper itself

Abstract

Etomidate (ET), a medical anesthetic, is increasingly being incorporated into e-liquids for consumption and abuse as a new psychoactive substance (NPS), leading to significant social issues. In this work, large-area Au micro- and nano-structured ordered arrays were engineered as surface-enhanced Raman spectroscopy (SERS) substrates for fast detection and precise identification of ET and its metabolites. This ordered array, characterized by abundant electromagnetic enhancement hotspots and structural uniformity, imparts unique properties to the SERS substrate, including ultra-sensitivity, spectral signal reproducibility, and precise quantitative capabilities. Furthermore, it effectively mitigates interference from the complex matrix of e-liquids, facilitating the rapid detection of trace amounts of ET molecules. This SERS rapid detection technology can act as a preliminary screening method for gold-standard spectroscopic analysis, facilitating the on-site rapid screening of suspicious samples and thereby enabling efficient detection and precise verification.

Indexed as

Au ordered arraye-liquidetomidaterapid drug detectionSERSsurface-enhanced Raman spectroscopy

Identifiers

PMID39683346
PMCPMC11643652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.