Evidence map›Paper›PMID 39683288›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices.

James Hall, Subbareddy Mekapothula, Rebecca Coxhill, Dominic Craske, Adam M Varney, Gareth W V Cave, Samantha McLean

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Biogenic copper and copper oxide nanoparticles to combat multidrug-resistantBiotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  6. Engineering copper and copper-based materials for a post-antibiotic era.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James HallSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0009-0004-8314-5228
Subbareddy MekapothulaSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0003-0391-3721
Rebecca CoxhillSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0009-0001-0694-5473
Dominic CraskeSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0003-3564-4108
Adam M VarneySchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0002-5943-161X
Gareth W V CaveSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0002-4167-1332
Samantha McLeanSchool of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.ORCID 0000-0001-8551-4307

Funding

Nottingham Trent University Vice Chancellor's PhD studentship
6 · The paper itself

Abstract

Copper oxide nanoparticles (CuONPs) offer promising antimicrobial properties against a range of pathogens, addressing the urgent issue of antibiotic resistance. This study details the synthesis of glutamic acid-coated CuONPs (GA-CuONPs) and their functionalisation on medical-grade silicone tubing, using an oxysilane bonding agent. The resulting coating shows significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains, while remaining non-toxic to human cells and exhibiting stable adherence, without leaching. This versatile coating method can be applied during manufacturing, or for ad hoc modifications, enhancing the antimicrobial properties of medical devices.

Indexed as

3-mercaptopropyltrimethoxysilaneantimicrobial activityCDC reactorcopper oxide nanoparticlesESKAPE pathogensGlu–CuO nanoparticlesglutamic acidMPTMSmulti-drug resistancetissue culture

Identifiers

PMID39683288
PMCPMC11643601

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.