Evidence map›Paper›PMID 39683264›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Biocompatibility Analysis of the Silver-Coated Microporous Titanium Implants Manufactured with 3D-Printing Technology.

Maxim Shevtsov, Emil Pitkin, Stephanie E Combs, Natalia Yudintceva, Denis Nazarov, Greg Van Der Meulen, Chris Preucil, Michael Akkaoui, Mark Pitkin

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A Brief Review on Biomimetics 3D Printing Design.Biomimetics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maxim ShevtsovDepartment of Radiation Oncology, Technische Universität München (TUM), Klinikum Rechts der Isar, Ismaninger Str. 22, 81675 Munich, Germany.ORCID 0000-0002-8539-2239
Emil PitkinDepartment of Statistics and Data Science, The Wharton School, University of Pennsylvania, Philadelphia, PA 19104, USA.
Stephanie E CombsDepartment of Radiation Oncology, Technische Universität München (TUM), Klinikum Rechts der Isar, Ismaninger Str. 22, 81675 Munich, Germany.
Natalia YudintcevaLaboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences (RAS), 194064 Saint Petersburg, Russia.ORCID 0000-0002-7357-1571
Denis NazarovSaint Petersburg State University, Universitetskaya Nab, 7/9, 199034 Saint Petersburg, Russia.ORCID 0000-0002-6254-7218
Greg Van Der MeulenMovora, St. Augustine, FL 32095, USA.
Chris PreucilMovora, St. Augustine, FL 32095, USA.
Michael AkkaouiTanury Industries, Lincoln, RI 02865, USA.
Mark PitkinDepartment of Orthopaedics and Rehabilitation Medicine, Tufts University School of Medicine, Boston, MA 02111, USA.

Funding

Validating establishment of functional safety in skin interface with deeply porous transcutaneous pylon for direct skeletal attachment of limb prosthesesR44AR079960 · NIAMS · POLY-ORTH INTERNATIONAL · PI PITKIN, MARK · 2021 to 2022
$1.7M
3D-printed Skin and Bone Integrated Pylon (SBIP-3D) for Direct Skeletal Attachment of Limb Prostheses.SB1AR086711 · NIAMS · POLY-ORTH INTERNATIONAL · PI Mark Pitkin · 2025 to 2026
$1.1M
National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH R44AR079960NIAMS NIH HHS R44 AR079960NIAMS NIH HHS SB1 AR086711
6 · The paper itself

Abstract

3D-printed microporous titanium scaffolds enjoy good biointegration with the residuum's soft and bone tissues, and they promote excellent biomechanical properties in attached prostheses. Implant-associated infection, however, remains a major clinical challenge. Silver-based implant coatings can potentially reduce bacterial growth and inhibit biofilm formation, thereby reducing the risk of periprosthetic infections. In the current study, a 1-µm thick silver coating was prepared on the surface of a 3D-printed microporous titanium alloy with physical vapor deposition (PVD), with a final silver content of 1.00 ± 02 mg/cm

Indexed as

3D printingbone tissue engineeringfibroblastsosseointegrationosteoblastsscaffoldssilver coatingtitanium alloy

Identifiers

PMID39683264
PMCPMC11643975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.