Integrated Metabolomic and Transcriptomic Analysis Reveal the Production Mechanism of Semicarbazide in

Jun Li, Di Wang, Shengjun Chen, Fangfang Gao, Chunsheng Li, Yang Feng, Jianchao Deng

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Effects of Sodium Hypochlorite Bleaching on the Quality and Safety of Basa (Foods (Basel, Switzerland) · 2026
Article
A Novel Strategy for the Detection of Semicarbazide in Crustaceans by Modified QuEChERS Coupled with Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry.Foods (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun LiGuangdong Provincial Key Laboratory of Lingnan Specialty Food Science and Technology, Key Laboratory of Green Processing and Intelligent Manufacturing of Lingnan Specialty Food, Ministry of Agriculture and Rural, College of Light Industry and Food, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.

Di WangKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.

Shengjun ChenKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.

Fangfang GaoKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.

Chunsheng LiKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.ORCID 0000-0003-1479-6831

Yang FengKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.

Jianchao DengKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China.

Funding

Central Public-interest Scientific Institution Basal Research Fund, CAFS NO. 2023TD78, NO. 2023TD74Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, China NYJG202304Key Laboratory of Processing and Nutritional Health of Tropical and Subtropical Aquatic Specialty Foods 2023KSYS006National Natural Science Foundation of China No. 32072147

6 · The paper itself

Abstract

Semicarbazide (SEM) is commonly utilized as a biomarker for detecting the usage of nitrofurazone (NFZ); however, its endogenous presence in aquatic products complicates detection and poses challenges to the quality and safety of these products. Although previous research suggests a potential link between SEM and urea, the specific mechanisms underlying its production under induced conditions remain unclear. To solve the above problem, the integrated metabolomic and transcriptomic analyses were performed for systematically exploring endogenous production mechanisms underlying SEM in

Indexed as

endogenous semicarbazideMacrobrachium rosenbergiimetabolomictranscriptomicurea

Identifiers

PMID39682889

DOI10.3390/foods13233817

PMCPMC11640138

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.