ArticleDiagnostics (Basel, Switzerland)2024
Diabetic Mastopathy: A Monocentric Study to Explore This Uncommon Breast Disease.
Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A Pictorial Review on Mastitis: Clinical Aspects, Imaging Features and Complications.Journal of imaging · 2026Review
- Multimodal Imaging of Diabetic Mastopathy: A 62-Case Study With Ultrasound-Based Classification and Diagnostic Accuracy.International journal of breast cancer · 2026Article
- Metachronous bilateral diabetic mastopathy mimicking breast cancer in a woman with long-standing type 2 diabetes: a case report.Frontiers in medicine · 2026Article
- Clinical-radiologic-pathologic characterization of diabetic mastopathy: an analysis of 21 cases.Frontiers in endocrinology · 2026Article
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8 authors.
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Abstract
backgroundDiabetic Mastopathy (DMP) is an uncommon benign fibro-inflammatory condition that occurs in women with long-standing diabetes mellitus (DM), particularly type 1. It often mimics breast cancer (BC) in clinical and imaging presentations, leading to diagnostic challenges.
methodsA retrospective monocentric study was conducted, analyzing clinical, radiologic, and pathological data from 28 women diagnosed with DMP over 10 years at the European Institute of Oncology. Data on DM type, age at DMP diagnosis, associated autoimmune conditions, imaging features, and surgical outcomes were collected and compared with the existing literature.
resultsThe majority (82%) of the patients had type 1 DM, with most diagnosed with DMP before age 40. Common complications included retinopathy (46%) and neuropathy (35%). Imaging often suggested malignancy, necessitating core needle biopsies for diagnosis. Surgical intervention occurred in 55% of cases, with a recurrence rate of 32%. One case of BC was observed.
conclusionsDMP remains challenging due to its resemblance to BC. Conservative management is typical, but the recurrence rate post-surgery highlights the importance of ongoing monitoring. Although DMP does not significantly increase BC risk, caution is advised, especially for immunocompromised patients. Further studies are needed to comprehensively understand DMP's relationship with BC.
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