Evidence map›Paper›PMID 39682572›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Clinical and Biological Markers of Frailty Syndrome in Patients Undergoing Elective Percutaneous Coronary Intervention.

Kristina Krivoshapova, Daria Tsygankova, Anastasiya Neeshpapa, Anastasia Kareeva, Alexandr Kokov, Evgeny Bazdyrev, Victoria Karetnikova, Olga Barbarash

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristina KrivoshapovaFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.ORCID 0000-0003-2384-5682
Daria TsygankovaFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.
Anastasiya NeeshpapaFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.
Anastasia KareevaFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.
Alexandr KokovFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.
Evgeny BazdyrevFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.ORCID 0000-0002-3023-6239
Victoria KaretnikovaFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.
Olga BarbarashFederal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo 650002, Russia.ORCID 0000-0002-4642-3610

Funding

The Russian Science Foundation. 22-15-00305
6 · The paper itself

Abstract

backgroundThe aim of this study was to analyze the prevalence of prefrailty and frailty syndrome (FS) in patients with coronary artery disease (CAD), and the clinical and biological characteristics of frail patients undergoing elective percutaneous coronary intervention (PCI). MATERIAL AND

methodsThe study included 78 patients with CAD who were admitted to the clinic to undergo PCI. To detect prefrailty and FS in patients, we used a short physical performance test battery (10-12 points-no FS, 8-9 points-prefrailty, 7 or fewer points-FS). We used the RayBio

resultsTaking into account the test battery score, the prevalence of FS in patients with CAD before elective PCI was 24.4%, the prevalence of prefrailty was 33.3%. According to the results of the study, older women with type 2 diabetes in their history were significantly more likely to be frail. Studying a wide range of biological markers of inflammation and musculoskeletal and fat remodeling, we noted lower levels of calcitonin (2.60 [1.50; 5.85] pg/mL,

conclusionThe results of the study confirm the high prevalence of prefrailty (33.3%) and FS (24.4%) in patients with CAD. Older women with type 2 diabetes in their history were significantly more likely to be frail. At the same time, the presence of FS is associated with lower levels of calcitonin and osteoprotegerin, and higher levels of leptin in the serum of frail patients before elective PCI.

Indexed as

biological markerscoronary artery diseasefrailty syndromepercutaneous coronary interventionprefrailty

Identifiers

PMID39682572
PMCPMC11640350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.