Evidence map›Paper›PMID 39682549›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Observational Analysis of Point-of-Care Lactate Plus™ Meter in Preclinical Trauma Models.

Catharina Gaeth, Jamila Duarte, Alvaro Rodriguez, Amber Powers, Randolph Stone

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catharina GaethCombat Wound Care, United States Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, Houston, TX 78234, USA.
Jamila DuarteCombat Wound Care, United States Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, Houston, TX 78234, USA.
Alvaro RodriguezCombat Wound Care, United States Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, Houston, TX 78234, USA.
Amber PowersCombat Wound Care, United States Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, Houston, TX 78234, USA.
Randolph StoneCombat Wound Care, United States Army Institute of Surgical Research, 3698 Chambers Pass, JBSA Fort Sam Houston, Houston, TX 78234, USA.ORCID 0000-0002-6000-3524

Funding

Unites States Army Medical Research and Development Command, Combat Casualty Care and Military Infection Disease Research Program P_10_2020_USAISR and CO220019
6 · The paper itself

Abstract

BACKGROUND/

objectivesBlood lactate concentration is often used to assess systemic hypoperfusion, tissue hypoxia, and sepsis in trauma patients and serves as a prognostic indicator and marker of response to therapy. Point-of-care (POC) devices provide rapid lactate measurements with a single drop of blood. In this study, lactate values from whole blood, measured with two POC devices, Abbott i-STAT

methodsAn observational analysis of 760 blood samples from four preclinical trauma animal models was performed. Lactate was measured simultaneously with two POC devices (i-STAT

resultsThe Spearman correlation was 0.9180 (95% CI 0.9056 to 0.9288) for i-STAT

conclusionsThe observed similarity in performance between the two devices suggests that both are capable of reliably measuring lactate levels in a trauma situation. The LA Plus™ meter provides fast results with only one drop of blood. This study supports the prehospital use of POC devices.

Indexed as

lactatepoint of carepreclinical trauma modelsprehospitalswinewhole blood

Identifiers

PMID39682549
PMCPMC11640412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.