Evidence map›Paper›PMID 39682542›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Should the Faecal Microbiota Composition Be Determined to Certify a Faecal Donor?

Celia Morales, Luna Ballestero, Patricia Del Río, Raquel Barbero-Herranz, Leticia Olavarrieta, Leticia Gómez-Artíguez, Javier Galeano, José Avendaño-Ortiz, Juan Basterra, Rosa Del Campo

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Celia MoralesMikrobiomik Healthcare Company, 48160 Vizcaya, Spain.
Luna BallesteroServicio de Microbiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Patricia Del RíoMikrobiomik Healthcare Company, 48160 Vizcaya, Spain.
Raquel Barbero-HerranzServicio de Microbiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-8845-1137
Leticia OlavarrietaUnidad Central de Apoyo (UCA-GT), Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Leticia Gómez-ArtíguezMikrobiomik Healthcare Company, 48160 Vizcaya, Spain.
Javier GaleanoGrupo de Sistemas Complejos, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
José Avendaño-OrtizServicio de Microbiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0003-2774-1821
Juan BasterraMikrobiomik Healthcare Company, 48160 Vizcaya, Spain.
Rosa Del CampoServicio de Microbiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0003-1147-7923

Funding

Mikrobiomik XX
6 · The paper itself

Abstract

BACKGROUND/

objectivesFaecal microbiota transplantation (FMT) is considered a safe and effective therapy for recurrent

methodsSamples from 10 certified donors from Mikrobiomik Healthcare Company were collected and sequenced using 16S rDNA in a MiSeq (Illumina) platform. Alpha (Chao1 and Shannon indices) and beta diversity (Bray-Curtis) were performed using the bioinformatic web server Microbiome Analyst. The differences in microbial composition at the genera and phyla levels among the donors were evaluated.

resultsThe microbial diversity metric by alpha diversity indexes showed that most donors exhibited a similar microbial diversity and richness, whereas beta diversity by 16S rDNA sequencing revealed significant inter-donor differences, with a more stable microbial composition over time in some donors. The phyla

Indexed as

16S rDNAfaecal microbiota transplantationhuman microbiome

Identifiers

PMID39682542
PMCPMC11640082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.