Evidence map›Paper›PMID 39682521›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Early Experience with Inner Branch Stent-Graft System for Endovascular Repair of Thoraco-Abdominal and Pararenal Abdominal Aortic Aneurysm.

Simone Cuozzo, Antonio Marzano, Ombretta Martinelli, Jihad Jabbour, Andrea Molinari, Vincenzo Brizzi, Enrico Sbarigia

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Semi-inner branch relining for late AFX type Ia/IIIa endoleak.Journal of vascular surgery cases and innovative techniques · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simone CuozzoVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1867-6151
Antonio MarzanoVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0009-0000-3881-8535
Ombretta MartinelliVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.
Jihad JabbourVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.
Andrea MolinariVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.
Vincenzo BrizziVascular Surgery Department, CHU de Bordeaux, 33000 Bordeaux, France.
Enrico SbarigiaVascular Surgery Division, Department of Surgery "Paride Stefanini", Policlinico Umberto I "La Sapienza" University of Rome, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the technical and clinical outcomes of the E-nside stent graft for thoraco-abdominal aortic aneurysm (TAAA) and pararenal abdominal aortic aneurysm (PAAA) endovascular treatment at our University Hospital Center.

methodsWe conducted a retrospective analysis of patients electively treated by inner branched EVAR (iBEVAR) between 05/2021 and 03/2023. Demographic, procedural, and clinical data were analyzed. The technical success and clinical outcomes, such as access-site-related complications were reported. The perioperative and early mortality rate, freedom from aortic reintervention, target vessels' (TVs) patency, and the endoleak rate were evaluated during the follow-up. The technical aspects (external iliac artery diameter, iliac tortuosity, extent of aortic coverage) were retrospectively analyzed.

resultsTwenty-two patients were included (age 75.9 ± 5.5; 72.7% male). The aneurism extent was Crawford I = 4 (18.2%), III = 8 (36.4%), IV = 5 (22.7%), V = 1 (4.5%), and PAAA = 4 (18.2%). The mean aortic diameter was 63.5 ± 9.9 mm. The technical success was 95.5% (assisted primary success 100%). The clinical success was 86.4%. The perioperative and early freedom from all-cause mortality rates were 90.9% and 90%, respectively. No case of inter-stage aortic-related mortality was reported, and there was no permanent/temporary spinal cord ischemia (SCI). Seventy-eight out of 81 patent TVs were incorporated through a bridging stent (96.3%). The TV success was 95.1%. The mean external iliac artery (EIA) diameter was 7.5 ± 1.1 mm. Twelve patients (54.5%, including all female patients) were considered outside the instructions for use (IFU) due to narrow iliac arteries. One access-site-related complication was reported.

conclusionsOur experience confirms that E-nside has promising technical and clinical success rates, as well as a low reintervention rate, but it requires a significant compromise of the healthy aortic tissue and adequate iliac arteries that still represents a limitation, especially among women. Mid- to long-term studies and prospective registries are mandatory to evaluate the long-term efficacy and safety, as a comparison between E-nside and other alternative off-the-shelf solutions.

Indexed as

branched stent graftE-nside multibranch stent–graft systeminner branchpararenal abdominal aortic aneurysm (PAAA)thoraco-abdominal aortic aneurysm (TAAA)

Identifiers

PMID39682521
PMCPMC11640084

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.