Feline Adenovirus Isolate Shows Silent Nucleotide Alterations, Alternative Receptor/Coreceptor Binding, High Resistance to Disinfectants and Antiviral Drugs, as Well as Immunomodulation.

Katalin Réka Tarcsai, Krisztián Bányai, Krisztina Bali, Anna Anoir Abbas, Valéria Kövesdi, József Ongrádi

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Katalin Réka TarcsaiDoctoral School, Semmelweis University, 1085 Budapest, Hungary.

Krisztián BányaiPathogen Discovery Group, HUN-REN Veterinary Medical Research Institute, 1143 Budapest, Hungary.

Krisztina BaliPathogen Discovery Group, HUN-REN Veterinary Medical Research Institute, 1143 Budapest, Hungary.

Anna Anoir AbbasDoctoral School, Semmelweis University, 1085 Budapest, Hungary.

Valéria KövesdiDepartment of Preventive Medicine and Public Health, Semmelweis University, 1085 Budapest, Hungary.

József OngrádiDepartment of Preventive Medicine and Public Health, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-0357-2878

Funding

National Research, Development and Innovation Office RRF-2.3.1-21-2022-00010 'National Laboratory of Virology'Semmelweis University Start-up Grant No. CO-11725

6 · The paper itself

Abstract

Adenovirus (AdV) infection has been rarely documented in cats and other felids. Partial sequences of the hexon and fiber genes of a Hungarian feline adenovirus isolate (FeAdV isolate) showed a close relationship to human AdV (HAdV) type C1. Further molecular and biological characterization is reported here. Whole-genome sequencing revealed two silent mutations in the genome of the FeAdV isolate compared to a HAdV-C1 reference strain (at positions 14,096 and 15,082). Competitive antibody binding to the Coxsackie-adenovirus receptor and α

Indexed as

antiviral therapycytokine productionfeline adenovirusphysico-chemical effectsreceptorswhole-genome sequencing

Identifiers

PMID39682467

DOI10.3390/ani14233502

PMCPMC11640234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.