Evidence map›Paper›PMID 39682465›Full record

ArticleAnimals : an open access journal from MDPI2024

Characteristics of Cerebrovascular Response to Intrinsic Vasoactive Substances in Sika Deer (

Md Zahorul Islam, Siyuan Wu, Tomoki Ootawa, Henry Smith, Ha Thi Thanh Nguyen, Etsumori Harada, Atsushi Miyamoto

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Md Zahorul IslamDepartment of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0003-4253-6711
Siyuan WuDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-5950-3433
Tomoki OotawaDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0009-0000-1243-0698
Henry SmithDepartment of Basic Veterinary Science, Joint Graduate School of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Ha Thi Thanh NguyenDepartment of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Gia Lam, Hanoi 131000, Vietnam.ORCID 0000-0003-2059-7492
Etsumori HaradaDepartment of Veterinary Physiology, Faculty of Agriculture, Tottori University, 4-101 Minami, Koyama-cho, Tottori 680-8553, Japan.
Atsushi MiyamotoDepartment of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-1980-2869

Funding

Japan Society for the Promotion of Science 16580242National Foundation for Science and Technology Development 09/2019/TN
6 · The paper itself

Abstract

Gravity may exert species-specific effects on quadrupedal vasoreactivity, reflecting variations in the vertical displacement of the cardiocranial axis from the dorsal plane. Deer show markedly displaced cardiocranial axes compared to their closest phylogenetic relatives, but their relative cerebrovascular responses remain unelucidated. Accordingly, we investigated the responses to noradrenaline (NA), acetylcholine (ACh), 5-hydroxytryptamine (5-HT), histamine, angiotensin (Ang) II, and bradykinin (BK) in cervine basilar arterial rings. NA and 5-HT induced slight contraction, and ACh induced relaxation, which contrasts with the findings reported in pigs and cattle. The cumulative response to ACh was abolished by endothelial denudation and inhibited by

Indexed as

acetylcholinebasilar arterydeergravityhistaminenoradrenaline

Identifiers

PMID39682465
PMCPMC11640203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.