Evaluation of Serum YKL-40 in Canine Multicentric Lymphoma: Clinical and Diagnostic Implications.

Chien-Chun Kuo, Jih-Jong Lee, Shang-Lin Wang, Yuan-Yuan Xia, Albert Taiching Liao

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chien-Chun KuoDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, No. 1 Sec. 4, Roosevelt Rd., Taipei City 106319, Taiwan.ORCID 0009-0002-5161-1859

Jih-Jong LeeInstitute of Veterinary Clinical Science, School of Veterinary Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei City 106319, Taiwan.ORCID 0000-0002-4424-730X

Shang-Lin WangInstitute of Veterinary Clinical Science, School of Veterinary Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei City 106319, Taiwan.ORCID 0000-0002-2390-1632

Yuan-Yuan XiaDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, No. 1 Sec. 4, Roosevelt Rd., Taipei City 106319, Taiwan.ORCID 0000-0001-7040-8341

Albert Taiching LiaoDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, No. 1 Sec. 4, Roosevelt Rd., Taipei City 106319, Taiwan.ORCID 0000-0002-8696-8180

Funding

Ministry of Science and Technology, Taiwan 109-2313-B-002-013

6 · The paper itself

Abstract

YKL-40, a secretory glycoprotein, is known as a prognostic biomarker in human cancers, but its role in canine multicentric lymphoma is not well understood. This study aimed to investigate serum YKL-40 levels in thirty dogs with multicentric lymphoma to determine their prognostic value, association with patient characteristics, and potential to predict chemotherapy response. Serum samples were collected before, during, and after chemotherapy, and YKL-40 level was measured using ELISA. The results showed that the pretreatment serum YKL-40 levels were significantly higher in dogs with multicentric lymphoma (394.0 pg/mL,

Indexed as

biomarkercanine multicentric lymphomaprognosisYKL-40

Identifiers

PMID39682357

DOI10.3390/ani14233391

PMCPMC11639910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.