Evidence map›Paper›PMID 39682294›Full record

ArticleCancers2024

Influence of Tumor Laterality and Focality on Clinical Implications and Tumor Advancement in Well-Differentiated Thyroid Cancer.

Michał Miciak, Krzysztof Jurkiewicz, Anna Dziekiewicz, Szymon Biernat, Michał Kisiel, Beata Wojtczak, Dorota Diakowska, Krzysztof Kaliszewski

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michał MiciakDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.ORCID 0000-0001-6130-2270
Krzysztof JurkiewiczDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.ORCID 0000-0003-0492-9020
Anna DziekiewiczDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.
Szymon BiernatDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.
Michał KisielDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.ORCID 0000-0002-7646-2354
Beata WojtczakDepartment of Endocrine Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.
Dorota DiakowskaDivision of Medical Biology, Faculty of Nursing and Midwifery, Wroclaw Medical University, 50-368 Wrocław, Poland.ORCID 0000-0002-1377-5601
Krzysztof KaliszewskiDepartment of General Surgery, University Centre of General and Oncological Surgery, Wroclaw Medical University, 50-556 Wrocław, Poland.ORCID 0000-0002-3291-5294

Funding

Wroclaw Medical University SUBZ.A440.24.009
6 · The paper itself

Abstract

backgroundThe accurate preoperative diagnosis of TC plays a very important role in the selection of an appropriate treatment strategy. In addition to the hypoechogenicity of thyroid lesions on ultrasound and the presence of microcalcifications or high cell atypia on FNAB, highlighting the features of laterality and focality and ascertaining their influence (alone or combined) on TC staging and appropriate treatment are crucial. MATERIALS AND

methodsA retrospective analysis of the clinical data of 697 patients admitted to the study center between 2008 and 2023 was conducted. Preoperative data (age, sex, type of surgery, ultrasound, and FNAB data) and postoperative histopathological data indicating TC advancement (pTNM, extrathyroidal extension, vascular invasion) were collected and analyzed. Patients presenting well-differentiated TCs (papillary TC and follicular TC) were isolated for better clinical evaluation. Finally, patients were divided into four groups according to their laterality and focality features, and the influences of combinations of these features on TC advancement were analyzed.

resultsThe largest group included patients with unilateral and solitary TC (

conclusionsLaterality and focality features may be important parameters in the management of TC and should be accurately determined. These features should be combined and a more aggressive treatment method should be selected to reduce the reoperation rate.

Indexed as

thyroid cancerthyroid cancer diagnosticsthyroid cancer managementthyroid surgerytumor focalitytumor laterality

Identifiers

PMID39682294
PMCPMC11640547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.