Evidence map›Paper›PMID 39682206›Full record

ArticleCancers2024

Alu-Mediated Duplication and Deletion of Exon 11 Are Frequent Mechanisms of

Diletta Sidoti, Valeria Margotta, Diletta Calosci, Erika Fiorentini, Costanza Bacci, Francesca Gensini, Laura Papi, Marco Montini

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Neurofibromin 1 (International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diletta SidotiDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.
Valeria MargottaDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.
Diletta CalosciDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.
Erika FiorentiniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.
Costanza BacciMedical Genetics Unit, SOS Day-Service Palagi, USL Toscana Centro, 50122 Florence, Italy.
Francesca GensiniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.ORCID 0000-0001-6669-420X
Laura PapiDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.ORCID 0000-0003-4552-9517
Marco MontiniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.ORCID 0000-0001-8407-0740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveLarge genomic rearrangements of

methodsBy using next-generation sequencing, we identified one duplication and three deletions of

resultsOur analysis revealed a tandem duplication of 5134 base pairs (bp) mediated by

conclusionsThis study underscores the remarkable instability of intronic regions flanking exon 11 of

Indexed as

Alu repeatsbreast cancerlarge genomic rearrangementsPALB2

Identifiers

PMID39682206
PMCPMC11640139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.