Evidence map›Paper›PMID 39682167›Full record

ArticleCancers2024

Discovery, Validation and Mechanistic Study of XPO1 Inhibition in the Treatment of Triple-Negative Breast Cancer.

Amy L Paulson, Robert F Gruener, Adam M Lee, R Stephanie Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amy L PaulsonDepartment of Molecular Pharmacology and Therapeutics, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.ORCID 0000-0001-9188-3969
Robert F GruenerDepartment of Experimental and Clinical Pharmacology, University of Minnesota School of Pharmacy, Minneapolis, MN 55455, USA.
Adam M LeeDepartment of Experimental and Clinical Pharmacology, University of Minnesota School of Pharmacy, Minneapolis, MN 55455, USA.
R Stephanie HuangDepartment of Molecular Pharmacology and Therapeutics, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.ORCID 0000-0002-9862-0368

Funding

TRAINING GRANT IN MICROBIOLOGY/CANCER RESEARCHT32CA009138 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Scott M. Dehm · 1985 to 2026
$11.3M
Genetic mechanisms underlying sexual dimorphism in cancer and response to therapyR01CA229618 · NCI · UNIVERSITY OF COLORADO DENVER · PI HUANG, RONG STEPHANIE, STRANGER, BARBARA E · 2019 to 2024
$2.9M
Drug repurposing in breast cancerR01CA204856 · NCI · UNIVERSITY OF MINNESOTA · PI HUANG, RONG STEPHANIE · 2018 to 2022
$2.2M
NCI NIH HHS R01 CA204856NCI NIH HHS R01 CA229618NCI NIH HHS T32 CA009138NIH/NCI R01CA204856
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NFKBIARNA-seqselective inhibitors of nuclear export (SINEs)triple-negative breast cancer (TNBC)XPO1

Identifiers

PMID39682167
PMCPMC11640544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.