Evidence map›Paper›PMID 39682109›Full record

ReviewCancers2024

The Role of Radiation, Immunotherapy, and Chemotherapy in the Management of Locally Advanced or Metastatic Cutaneous Malignancies.

Irini Yacoub, Kareem Rayn, J Isabelle Choi, Richard Bakst, Arpit Chhabra, Joshua Y Qian, Peter Johnstone, Charles B Simone

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irini YacoubNew York Proton Center, New York, NY 10035, USA.
Kareem RaynDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
J Isabelle ChoiNew York Proton Center, New York, NY 10035, USA.
Richard BakstNew York Proton Center, New York, NY 10035, USA.
Arpit ChhabraNew York Proton Center, New York, NY 10035, USA.
Joshua Y QianDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-3094-9052
Peter JohnstoneDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0003-4221-9388
Charles B SimoneNew York Proton Center, New York, NY 10035, USA.ORCID 0000-0002-0867-3694

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

introductionSkin cancer impacts a significant proportion of the population. While surgical management is often the mainstay of treatment, advanced or metastatic cutaneous malignancies require additional local and/or systemic therapies.

methodsA review of the literature was performed studying the use of radiation therapy, chemotherapy, and immunotherapy for locally advanced or metastatic cutaneous malignancies.

resultsA summary of the present literature on the management of locally advanced or metastatic cutaneous malignancies is presented across cutaneous head and neck basal cell carcinoma, squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The addition of multidisciplinary therapies to resection is often associated with improved outcomes.

conclusionThe management of cutaneous head and neck malignancies requires an approach integrating multiple specialties, to optimize outcomes and minimize toxicities.

Indexed as

basal cellcutaneousimmunotherapymelanomaMerkel cellradiotherapysquamous cellsystemic therapy

Identifiers

PMID39682109
PMCPMC11640331

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.