Evidence map›Paper›PMID 39681882›Full record

ArticleTranslational neurodegeneration2024

Recombinant SMN protein synergizes with spinal muscular atrophy therapy to counteract pathological motor neuron phenotypes.

Liliana Brambilla, Chiara F Valori, Giulia Guidotti, Francesca Martorana, Claudia Sulmona, Lisa Benedetta De Martini, Anselmo Canciani, Marco Fumagalli, Francesca Talpo, Gerardo Biella and 5 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational neurodegeneration, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Liliana BrambillaLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Chiara F ValoriLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Giulia GuidottiLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Francesca MartoranaLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Claudia SulmonaLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Lisa Benedetta De MartiniLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Anselmo CancianiThe Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
Marco FumagalliThe Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
Francesca TalpoDepartment of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
Gerardo BiellaDepartment of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
Elisa Di PasqualeHumanitas Cardio Center, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
Claudio IacobucciDepartment of Physical and Chemical Sciences, University of L'Aquila, 67100, L'Aquila, Italy.
Federico FornerisThe Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
Haiyan ZhouDubowitz Neuromuscular Centre and National Institute for Health Research, Great Ormond Street Institute of Child Health, Biomedical Research Centre, University College London, London, UK.
Daniela RossiLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy. daniela.rossi@icsmaugeri.it.ORCID http://orcid.org/0000-0002-3346-1327

Funding

AFM-Téléthon 16177AFM-Téléthon 18221AFM-Téléthon 21565Associazione Italiana per la Ricerca sul Cancro Bridge 27004Associazione Italiana per la Ricerca sul Cancro MFAG 20075Giovanni Armenise-Harvard Foundation CDA 2013Velux Stiftung 1375
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39681882
PMCPMC11650830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.