Evidence map›Paper›PMID 39681809›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2025

Orthostatic test shows higher systolic blood pressure and sympathetic response in uncomplicated type 1 diabetes patients with normal V̇O

Samu Sorola, Vesa Hyrylä, Timo Eronen, Saana Kupari, Mika Venojärvi, Heikki Tikkanen, Mika Tarvainen, Harri Lindholm

Abstract read
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samu SorolaInstitute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland. samu.jonne.sorola@gmail.com.ORCID http://orcid.org/0000-0001-8713-7365
Vesa HyryläDepartment of Technical Physics, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-4696-2307
Timo EronenInstitute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0009-0004-2622-3971
Saana KupariDepartment of Technical Physics, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-9168-8159
Mika VenojärviInstitute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0003-1327-9760
Heikki TikkanenInstitute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0001-6067-4101
Mika TarvainenDepartment of Technical Physics, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0001-8686-5395
Harri LindholmInstitute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-1565-0909

Funding

European Foundation for the Study of Diabetes 96108
6 · The paper itself

Abstract

purposeCardiovascular autonomic neuropathy remains underdiagnosed in type 1 diabetes mellitus, posing a risk for severe complications, particularly in patients with lowered V̇O

methodsA type 1 diabetes mellitus group (n = 14) with no other diagnosed diseases (diabetes duration 15 ± 7 years) and a control group (n = 31) underwent deep breathing test, passive orthostatic test, and cardiopulmonary exercise test. Participants were assessed for heart rate variability, heart rate, blood pressure, and V̇O

resultsParticipant characteristics, including V̇O

conclusionPatients with uncomplicated type 1 diabetes mellitus, despite having normal cardiorespiratory fitness, exhibited higher systolic pressure and greater sympathetic activation in orthostatic tests, suggesting subclinically altered cardiovascular autonomic function.

Indexed as

Blood PressureDiabetes Mellitus, Type 1Oxygen ConsumptionSympathetic Nervous SystemAdultExercise TestFemaleHeart RateHumansMaleYoung AdultCardiorespiratory fitnessDeep breathing testHeart rate variabilityOrthostatic testType 1 diabetes

Identifiers

PMID39681809
PMCPMC12137366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.