Evidence map›Paper›PMID 39681774›Full record

ArticleMolecular imaging and biology2025

Jie Gao, Yao Fu, Kuiqiang He, Qinfeng Xu, Feng Wang, Hongqian Guo

Abstract read
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In one paragraph

Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie Gao *Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Institute of Urology Nanjing University, Jiangsu, China.
Yao Fu *Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Jiangsu, China.
Kuiqiang He *Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Institute of Urology Nanjing University, Jiangsu, China.
Qinfeng XuDepartment of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China.
Feng WangDepartment of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China. fengwangcn@hotmail.com.
Hongqian GuoDepartment of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Institute of Urology Nanjing University, Jiangsu, China. dr.ghq@nju.edu.cn.ORCID http://orcid.org/0000-0002-3121-5157

Funding

the China Postdoctoral Science Foundation 2022M711579the National Natural Science Foundation of China 81972388, 82103002the Natural Science Foundation of Jiangsu Province BE2020622the Sino-German Mobility Programme M-0670
6 · The paper itself

Abstract

purposeTo develop a novel risk model incorporating

methodsThe study retrospectively enrolled 192 PCa patients with preoperative multiparametric MRI,

resultsWith the median peritumoral nerve density of 6, patients were stratified as low-PNI group (nerve density < 6, n = 78, 40.6%) and high-PNI group (nerve density ≥ 6, n = 114, 59.4%). Compared with low-PNI PCa, high-PNI PCa harbored significantly larger imaging lesion diameter (P < 0.001), higher PI-RADS score (P = 0.009), higher SUVmax (P < 0.001), larger tumor diameter (P = 0.024) and higher Gleason grade group (P < 0.001). Further, with univariate and multivariate analyses, imaging lesion diameter (OR 2.98, 95% CI 1.73-5.16, P = 0.004) and SUVmax (OR 3.59, 95%CI 2.32-5.55, P < 0.001) and were identified as independent predictors for PNI in PCa, and a PNI-risk nomogram incorporating these two predictors was constructed. The PNI-risk nomogram demonstrated considerable calibration (mean absolute error 0.026) and discrimination (area under the curve = 0.889, sensitivity 73.1%, specificity 97.4%) abilities, harboring net benefits with threshold probabilities range from 0 to 0.80.

conclusion

Indexed as

Edetic AcidOligopeptidesPeripheral NervesPositron Emission Tomography Computed TomographyProstatic NeoplasmsAgedGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedNeoplasm InvasivenessNomogramsRetrospective StudiesROC CurveEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptides68Ga-PSMA PET/CTNerveNomogramPerineural InvasionProstate Cancer

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.