ArticleScientific reports2024
Interaural level difference sensitivity in neonatally deafened rats fitted with bilateral cochlear implants.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Neurophysiological sensitivity to envelope and pulse timing interaural time differences in cochlear implanted rats with different hearing experiences.The Journal of physiology · 2026Article
- Binaural sensitivity and processing of envelope-based interaural difference cues by bilateral cochlear implant users with perilingual and postlingual onset of deafness.The Journal of the Acoustical Society of America · 2026Article
- Interactions of Interaural Time and Level Differences in Spatial Hearing with Cochlear Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Pulse timing dominates binaural hearing with cochlear implants.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- When the First Pulse Fades: 75% Reduction in Precedence Effect in Cochlear Implanted Rats.Trends in hearingArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bilateral cochlear implant (CI) patients exhibit significant limitations in spatial hearing. Their ability to process interaural time differences (ITDs) is often impaired, while their ability to process interaural level differences (ILDs) remains comparatively good. Clinical studies aiming to identify the causes of these limitations are often plagued by confounds and ethical limitations. Recent behavioral work suggests that rats may be a good animal model for studying binaural hearing under neuroprosthetic stimulation, as rats develop excellent ITD sensitivity when provided with suitable CI stimulation. However, their ability to use ILDs has not yet been characterized. Objective of this study is to address this knowledge gap. Neontally deafened rats were bilaterally fitted with CIs, and trained to lateralize binaural stimuli according to ILD. Their behavioral ILD thresholds were measured at pulse rates from 50 to 2400 pps. CI rats exhibited high sensitivity to ILDs with thresholds of a few dB at all tested pulse rates. We conclude that early deafened rats develop good sensitivity, not only to ITDs but also to ILDs, if provided with appropriate CI stimulation. Their generally good performance, in line with expectations from other mammalian species, validates rats as an excellent model for research on binaural auditory prostheses.
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