Evidence map›Paper›PMID 39681592›Full record

ArticleScientific reports2024

Antibacterial, antioxidant, cytotoxicity, and phytochemical screening of Moringa oleifera leaves.

Gamal M El-Sherbiny, Amira J Alluqmani, Islam A Elsehemy, Mohamed H Kalaba

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
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  6. Article
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  20. Green Synthesis of AgNPs fromNanomaterials (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gamal M El-SherbinyBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt. gamalelsherbiny1970@azhar.edu.eg.ORCID 0000-0003-3968-0536
Amira J AlluqmaniBiology Department, Umm Al-Qura University, 21421, Makkah, Saudi Arabia.
Islam A ElsehemyChemistry of Natural and Microbial Products, National Research Centre, Giza, Egypt.
Mohamed H KalabaBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial resistance to antibiotics remains a significant clinical challenge, contributing to persistently high rates of morbidity and mortality. Achieving treatment success is increasingly difficult, necessitating the evaluation of new antibiotics and complementary approaches, including source control and alternative therapies. This study aimed to investigate the antibacterial, antioxidant, cytotoxic, and phytochemical properties of Moringa oleifera leaf extract using high-performance liquid chromatography (HPLC), and to evaluate the pharmacokinetic properties of its major compound. The extract demonstrated strong antibacterial activity against standard strains and foodborne bacterial species. It also showed significant antioxidant potential, supported by the presence of high concentrations of phenolic and flavonoid compounds. HPLC analysis identified multiple bioactive compounds, with quercetin as the predominant component. The cytotoxicity study confirmed the safety of the extract at low and moderate concentrations, and ADMET analysis indicated favorable pharmacokinetic characteristics of quercetin. In conclusion, Moringa oleifera exhibits promising potential for medical and food industry applications due to its significant antibacterial and antioxidant activities, combined with a strong safety profile and rich phytochemical content.

Indexed as

Anti-Bacterial AgentsAntioxidantsMoringa oleiferaPhytochemicalsPlant ExtractsPlant LeavesAnimalsBacteriaChromatography, High Pressure LiquidFlavonoidsHumansMicrobial Sensitivity TestsPhenolsQuercetinAnti-Bacterial AgentsAntioxidantsFlavonoidsPhenolsPhytochemicalsPlant ExtractsQuercetinADMET analysisAntibacterialAntioxidantCytotoxicityMoringa oleiferaPhytochemical compositionsQuercetin

Identifiers

PMID39681592
PMCPMC11649684

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.