Evidence map›Paper›PMID 39681357›Full record

GuidelineAnnals of laboratory medicine2025

Clinical Pharmacogenetic Testing and Application: 2024 Updated Guidelines by the Korean Society for Laboratory Medicine.

John Hoon Rim, Young-Gon Kim, Sollip Kim, Rihwa Choi, Jee-Soo Lee, Seungman Park, Woochang Lee, Eun Young Song, Soo-Youn Lee, Sail Chun and 1 more

Abstract readPractice Guideline
In one paragraph

Guideline in Annals of laboratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Distribution ofFrontiers in genetics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John Hoon RimDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-6825-8479
Young-Gon KimDepartment of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID 0000-0001-6840-6830
Sollip KimDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-0474-5897
Rihwa ChoiDepartment of Laboratory Medicine, GC Labs, Yongin, Korea.ORCID 0000-0002-8266-2248
Jee-Soo LeeDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0002-6633-4631
Seungman ParkDepartment of Laboratory Medicine, National Cancer Center, Goyang, Korea.ORCID 0000-0003-2123-3711
Woochang LeeDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-3956-6397
Eun Young SongDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0003-1286-9611
Soo-Youn LeeDepartment of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID 0000-0001-7595-4042
Sail ChunDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-5792-973X
Pharmacogenetics Guideline Task-Force Team of the Korean Society for Laboratory Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the era of precision medicine, pharmacogenetics has substantial potential for addressing inter-individual variability in drug responses. Although pharmacogenetics has been a research focus for many years, resulting in the establishment of several formal guidelines, its clinical implementation remains limited to several gene-drug combinations in most countries, including Korea. The main causes of delayed implementation are technical challenges in genotyping and knowledge gaps among healthcare providers; therefore, clinical laboratories play a critical role in the timely implementation of pharmacogenetics. This paper presents an update of the Clinical Pharmacogenetic Testing and Application guidelines issued by the Korean Society for Laboratory Medicine and aims to provide the necessary information for clinical laboratories planning to implement or expand their pharmacogenetic testing. Current knowledge regarding nomenclature, gene-drug relationships, genotyping technologies, testing strategies, methods for clinically relevant information delivery, QC, and reimbursements has been curated and described in this guideline.

Indexed as

PharmacogeneticsPharmacogenomic TestingGenotypeGenotyping TechniquesHumansPrecision MedicineRepublic of KoreaClinical laboratoryGuidelineKoreaPharmacogeneticsPharmacogenetic testing

Identifiers

PMID39681357
PMCPMC11788703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.