Evidence map›Paper›PMID 39680266›Full record

ArticleCell and tissue banking2024

Development of a sterilization process for amniotic membrane allograft tissue using supercritical carbon dioxide and NovaKill.

Jennifer O'Connell, Komali Pentakota, Donny Villeareal, Jose Faz, Xiaoli Li, Anthony Trinh, Rachel Beddard, Scott Jones, Anand Srinivasan

Abstract read
In one paragraph

Article in Cell and tissue banking, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer O'ConnellThe Center for Innovations and Biodesign, San Antonio, TX, USA.
Komali PentakotaThe Center for Innovations and Biodesign, San Antonio, TX, USA.
Donny VillearealBioBridge Global, Research and Development, San Antonio, TX, USA.
Jose FazBioBridge Global, Research and Development, San Antonio, TX, USA.
Xiaoli LiBioBridge Global, Research and Development, San Antonio, TX, USA.
Anthony TrinhBioBridge Global, Research and Development, San Antonio, TX, USA.
Rachel BeddardBioBridge Global, Research and Development, San Antonio, TX, USA.
Scott JonesBioBridge Global, Research and Development, San Antonio, TX, USA.
Anand SrinivasanThe Center for Innovations and Biodesign, San Antonio, TX, USA. Anand.Srinivasan@BioBridgeGlobal.org.

Funding

BioBridge Global BBGCIBRD2023
6 · The paper itself

Abstract

Amniotic membrane is arguably one of the most popular biological wound dressings on the market today. Various growth factors and cytokines inherent to amniotic membrane tissue have been recognized as key mediators in wound healing and tissue regeneration, giving the tissue its clinical utility. Sterilization methodologies using irradiation are recognized as the gold standard in the field and routinely used to prepare tissue allografts, including amniotic membrane for transplantation. However, irradiation is not always compatible in preserving the physical structure or biochemical factors of biological materials and can potentially result in detrimental effects to the critical quality attributes of allograft tissues. Alternatively, a novel sterilization technique involving supercritical carbon dioxide (SCCO

Indexed as

AllograftsAmnionCarbon DioxideSterilizationHumansIntercellular Signaling Peptides and ProteinsCarbon DioxideIntercellular Signaling Peptides and ProteinsAmniotic membrane allograft tissueIrradiationSpore inactivationSterilizationSupercritical carbon dioxideValidation

Identifiers

PMID39680266
PMCPMC11649788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.