Evidence map›Paper›PMID 39680236›Full record

ArticleJournal of neurology2024

Auditory processing deficits in subacute stroke.

Jawad Abdulla, Nehzat Koohi, Rahul Lakshmanan, Chandrashekar Hoskote, Menelaos Pavlou, Jason D Warren, Chris J D Hardy, David J Werring, Doris-Eva Bamiou

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In one paragraph

Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jawad Abdulla *Department of Neuro-Otology, Royal National ENT and Eastman Dental Hospitals, London, UK.
Nehzat Koohi *Department of Clinical and Movement Neurosciences, University College London, Queen Square Institute of Neurology, London, UK.
Rahul LakshmananDepartment of Medical Imaging, Perth Children's Hospital, Perth, Australia.
Chandrashekar HoskoteNeuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
Menelaos PavlouDepartment of Statistical Science, University College London, London, UK.
Jason D WarrenDementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
Chris J D HardyStroke Research Centre, Department of Brain Repair and Rehabilitation, University, College London Queen Square Institute of Neurology, London, UK.
David J WerringComprehensive Stroke Service, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
Doris-Eva BamiouThe Ear Institute, University College London, London, UK. d.bamiou@ucl.ac.uk.ORCID http://orcid.org/0000-0001-7486-4264

Funding

National Institute on Handicapped Research NIHR302201
6 · The paper itself

Abstract

backgroundStroke is the second leading cause of disability worldwide. Stroke results in focal neurological deficit and often leads to auditory problems due to its impact on the auditory pathway. Altered connections in the auditory pathway, caused by stroke, can result in hearing difficulties ranging from impaired sound detection to altered auditory perception. A better understanding of how stroke affects these early sound processing mechanisms will provide valuable insights into stroke recovery and rehabilitation options.

methodsWe recruited forty consecutive adult patients with stroke (30 males, 10 females) due to ischemic or intracerebral hemorrhage > 3 and up to 12 months after stroke (subacute stage). Brain MRIs were performed on all patients, and we calculated a central auditory nervous system stroke severity index (CANS SSI) according to number of CANS areas involved and an extended CANS definition of auditory responsive areas. All patients underwent cognitive screening assessment, basic audiological assessments, and a hierarchical central auditory processing assessment battery with the Queen Square Tests of Auditory Cognition (early perceptual processing, apperceptive processing, semantic Processing) and Gaps in Noise tests.

resultsWhen comparing patients with auditory responsive cortical lesions and with versus without Heschl's gyrus involvement (primary auditory cortex), patients with Heschl's gyrus involvement exhibited worse early perceptual scores. The CANS SSI showed a significant negative correlation with early perceptual test scores.

conclusionThis study demonstrates a correlation between stroke severity, characterized by a higher number of lesions involving auditory areas in patients with subacute stroke, and worse early perceptual scores. Heschl's gyrus involvement is associated with poorer early perceptual score.

Indexed as

Auditory Perceptual DisordersMagnetic Resonance ImagingStrokeAcoustic StimulationAdultAgedAuditory CortexAuditory PerceptionFemaleHumansMaleMiddle AgedSeverity of Illness IndexAuditory processing disorderCentral auditory nervous systemHearing lossStroke

Identifiers

PMID39680236
PMCPMC11649831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.