Evidence map›Paper›PMID 39680189›Full record

ArticleArchives of orthopaedic and trauma surgery2024

Enhancing treatment outcomes for Acute Periprosthetic Hip Joint infection: optimizing debridement, antibiotics, and Implant Retention through vacuum sealing drainage in the deep tissue.

Ling-Chuan Gu, Yang Peng, Ying Zhang, Xiao-Yuan Gong, Tiao Su, Guang-Xing Chen

Abstract read
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In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ling-Chuan Gu *Center for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China.
Yang Peng *Center for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China.
Ying ZhangCenter for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China.
Xiao-Yuan GongCenter for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China. xiaoyuangong123@tmmu.edu.cn.
Tiao SuCenter for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China. hhhhst@tmmu.edu.cn.
Guang-Xing ChenCenter for Joint Surgery, Intelligent Manufacturing and Rehabilitation Engineering Center, Southwest Hospital, Army Medical University, Gaotanyan Street, Chongqing, 400038, China. cgx7676@tmmu.edu.cn.

Funding

National Natural Science Foundation of China 82372365Natural Science Foundation of Chongqing Municipality CSTB2022NSCQ-LZX0066
6 · The paper itself

Abstract

backgroundDebridement, antibiotics, and implant retention (DAIR) for acute periprosthetic joint infection (PJI) is under debated since the reported success rate is inconsistent. This study aimed to explore the efficacy of vacuum sealing drainage (VSD) used as an adjunct to irrigation and debridement for acute PJI.

methodsPatients undergoing debridement, irrigation with component retention, and application of vacuum seal drainage in the deep portion surrounding the infected sites from January 2014 to February 2021 were retrospectively reviewed. The definition of failure included the requirement of prosthesis removal; persistent infection-related symptoms; suppressive antibiotics therapy due to failure of controlling the infection; infection-related death.

results45 patients were included in this study with a mean follow-up of 45.62 ± 13.87 months. There were 28 males and 17 females with a mean age of 63.29 ± 17.74 months. The overall success rate was 86.67% with 6 failures. Multivariate analysis revealed a significant association between Charlson comorbidity index and treatment failure (OR = 2.226, 95% CI, 1.057-4.687, p = 0.035).

conclusionsThe incorporation of VSD in the deeper region enhances the outcomes of DAIR, achieving an 86.67% success rate in managing acute PJI. This approach offers a potentially safe and effective treatment, though patients with higher Charlson comorbidity index and elevated preoperative CRP levels face increased risks of failure.

Indexed as

Anti-Bacterial AgentsDebridementProsthesis-Related InfectionsAcute DiseaseAgedArthroplasty, Replacement, HipDrainageFemaleHip ProsthesisHumansMaleMiddle AgedNegative-Pressure Wound TherapyProsthesis RetentionRetrospective StudiesTherapeutic IrrigationAnti-Bacterial AgentsAntibioticsDebridementPeriprosthetic joint infectionVacuum sealing drainage

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.