Evidence map›Paper›PMID 39680024›Full record

ReviewAccounts of chemical research2025

Lipid Trafficking in Diverse Bacteria.

Jonathan Chiu-Chun Chou, Laura M K Dassama

Abstract readReview
In one paragraph

Review in Accounts of chemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan Chiu-Chun ChouDepartment of Chemistry and Sarafan ChEM-H Institute, Stanford University, Stanford, California 94305, United States.
Laura M K DassamaDepartment of Chemistry and Sarafan ChEM-H Institute, Stanford University, Stanford, California 94305, United States.ORCID 0000-0002-0851-6373

Funding

Deciphering the molecular mechanisms of sterol lipid trafficking in bacteriaR35GM150910 · NIGMS · STANFORD UNIVERSITY · PI Laura Dassama · 2023 to 2026
$1.9M
NIGMS NIH HHS R35 GM150910
6 · The paper itself

Abstract

Lipids are essential for life and serve as cell envelope components, signaling molecules, and nutrients. For lipids to achieve their required functions, they need to be correctly localized. This requires the action of transporter proteins and an energy source. The current understanding of bacterial lipid transporters is limited to a few classes. Given the diversity of lipid species and the predicted existence of specific lipid transporters, many more transporters await discovery and characterization. These proteins could be prime targets for modulators that control bacterial cell proliferation and pathogenesis. One overarching goal of our research is to understand the molecular mechanisms of bacterial metabolite trafficking, including lipids, and to leverage that understanding to identify or engineer inhibitory ligands. In recent years, our work has revealed two novel lipid transport systems in bacteria: bacterial sterol transporters (Bst) A, B, and C in

Indexed as

BacteriaBacterial ProteinsBiological TransportLipid MetabolismMembrane Transport ProteinsBacterial ProteinsMembrane Transport Proteins

Identifiers

PMID39680024
PMCPMC11713862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.