Evidence map›Paper›PMID 39679968›Full record

ArticleClinical cardiology2024

Temporal Trends in Mortality Related to Stroke and Atrial Fibrillation in the United States: A 21-Year Retrospective Analysis of CDC-WONDER Database.

Owais Ahmad, Hanzala Ahmed Farooqi, Isra Ahmed, Adeena Jamil, Rayyan Nabi, Irfan Ullah, Abdul Wali Khan, Raheel Ahmed, Mahboob Alam, Bernardo Cortese and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Owais AhmadIslamic International Medical College, Riphah International University, Islamabad, Pakistan.
Hanzala Ahmed FarooqiIslamic International Medical College, Riphah International University, Islamabad, Pakistan.
Isra AhmedAga Khan University, Karachi, Pakistan.
Adeena JamilDepartment of Medicine, Dow International Medical College, Karachi, Pakistan.
Rayyan NabiIslamic International Medical College, Riphah International University, Islamabad, Pakistan.ORCID http://orcid.org/0009-0001-9409-652X
Irfan UllahDepartment of Internal Medicine, Khyber Teaching Hospital, Peshawar, Pakistan.ORCID https://orcid.org/0000-0003-1100-101X
Abdul Wali KhanDepartment of Internal Medicine, University of Missouri - Kansas City, Kansas City, Missouri, USA.
Raheel AhmedNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-2814-7314
Mahboob AlamDivision of Cardiology, Baylor College of Medicine, Houston, Texas, USA.
Bernardo CorteseHarrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Mamas A MamasKeele Cardiovascular Research Group, Keele University, Stoke on Trent, UK.

Funding

APC charges were funded by Imperial College London.
6 · The paper itself

Abstract

aimsAtrial Fibrillation (AF) is one of the most strongly associated risk factors for stroke. Our study aims to analyze changes in mortality from 1999 to 2020 in patients with AF and stroke.

methodsUsing the Centre for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC-WONDER), we retrospectively analyzed annual age-adjusted mortality rates (AAMR) per million from 1999 to 2020 in stroke patients with AF. Temporal trends were analyzed, and Annual Percentage Change (APC) was calculated using the JoinPoint regression model across variations in demographics (sex, race) and regional subgroups.

resultsAround 490 000 deaths were reported between 1999 and 2020 from stroke and AF across the 25-85+ age group. AAMR initially decreased until 2008 (APC = -0.9), followed by an increase till 2020 (APC = 1.1). Women had a higher AAMR than men throughout the years. Non-Hispanic white patients had a marginally higher AAMR than all other races and ethnicities. The highest AAMR was observed in the western region. States like Vermont, Oregon, Washington, Alaska, Minnesota, and West Virginia were in the top 90th percentile, while Nevada, Louisiana, Florida, New York, New Mexico, and Arizona were in the bottom 10th percentile. Nonmetropolitan areas had consistently higher AAMRs throughout the 2 decades.

conclusionAn overall rise in mortality has been observed in stroke and AF patients, with a greater surge in 2019. The need for healthcare policy changes, especially in areas with high mortality and awareness of healthier lifestyle factors, can be an essential preventative measure to help mitigate growing mortality rates.

Indexed as

Atrial FibrillationStrokeAdultAgedAged, 80 and overAge DistributionCenters for Disease Control and Prevention, U.S.Databases, FactualFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSurvival RateTime Factorsatrial fibrillationCDC wondermortalitystroketemporal trends

Identifiers

PMID39679968
PMCPMC11648035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.