Evidence map›Paper›PMID 39679937›Full record

ArticleJournal of the American Geriatrics Society2025

Frailty, social deprivation, and mortality among Medicare fee-for-service beneficiaries.

Lily Zhong, Stephanie Denise M Sison, Megan Cheslock, Yuchen Liu, Natalie Newmeyer, Dae Hyun Kim

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Application of Claims-based Frailty Index to a Structured Electronic Health Record Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lily ZhongUniversity of Connecticut School of Medicine, Farmington, Connecticut, USA.ORCID 0000-0001-8732-3192
Stephanie Denise M SisonHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Megan CheslockVeterans Affairs Bedford Healthcare System, Bedford, Massachusetts, USA.
Yuchen LiuHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-6231-4414
Natalie NewmeyerHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Dae Hyun KimHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-7290-6838

Funding

Applications of Claims-Based Frailty Index to Advance Evidence for Frailty-Guided Decision-Making - Extension to ADRDR01AG071809 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI KIM, DAE HYUN · 2021 to 2025
$3.5M
Greater Boston Medical Student Training in Aging ResearchT35AG038027 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI DRIVER, JANE A, MCLAUGHLIN-GAVIN, CARA · 2010 to 2024
$991k
Mid-Career Mentoring Award For Patient-Oriented Research in Frailty and Health OutcomesK24AG073527 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI Dae Hyun Kim · 2022 to 2026
$862k
NIA NIH HHS 5T35AG038027-12NIA NIH HHS K24 AG073527NIA NIH HHS K24AG073527NIA NIH HHS R01 AG071809NIA NIH HHS R01AG071809NIA NIH HHS T35 AG038027NIH HHS 5T35AG038027-12
6 · The paper itself

Abstract

backgroundThe geographic distribution of frailty and social deprivation, and their association with mortality in the United States, have not been well studied.

methodsWe estimated claims-based frailty index (CFI) (range: 0-1) and area-level social deprivation index (SDI) (range: 0-100) in a 5% random sample of 1,207,323 Medicare fee-for-service beneficiaries 65 years and older. We examined the prevalence of frailty (defined as CFI ≥ 0.25) and the mean SDI and estimated their correlation by state and county. The association of frailty and social deprivation with one-year mortality was estimated using logistic regression, adjusting for age, sex, and dual eligibility status.

resultsThe study population had the following characteristics: mean age of 76 years, 56% female, 10.3% with frailty, and 24.0% with high social deprivation (SDI ≥ 67). The correlation between frailty and social deprivation was weak (ρ = 0.39 by state and 0.28 by county). The risk of death for the total study population was 4.5%. The age, sex, dual eligibility, and SDI-adjusted risk of death for robust, pre-frail, and frail individuals was 1.8%, 4.4%, and 13.3%, respectively. The age, sex, dual eligibility-adjusted risk of death for low, medium, and high SDI regardless of frailty was 4.4%, 4.7%, and 4.6%, respectively. In robust beneficiaries, the adjusted risk of death for low, medium, and high social deprivation was 1.6%, 1.9% (odds ratio [OR]: 1.21 [95% confidence interval, CI: 1.15, 1.27]), and 2.0% (1.31 [1.24, 1.38]), respectively, whereas in beneficiaries with frailty, the corresponding risk by social deprivation was 13.4%, 13.7% (1.03 [0.99, 1.07]), and 12.9% (0.96 [0.92, 1.00]).

conclusionThis study identifies regions of the United States that may be most vulnerable from frailty and social deprivation. These findings emphasize the significance of frailty and social deprivation on mortality and the need for community-based preventative health programs such as frailty screening to improve health outcomes for Medicare beneficiaries living with frailty.

Indexed as

Fee-for-Service PlansFrail ElderlyFrailtyMedicareMortalitySocial DeprivationAgedAged, 80 and overFemaleHumansMalePrevalenceUnited Statesfrailtygeographic distributionMedicaremortalitysocial deprivation

Identifiers

PMID39679937
PMCPMC12101957

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.