Evidence map›Paper›PMID 39679800›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation.

Laiben Gao, Xiaoqiu Dou, Chao Xing, Kaikai Yang, Changli Zhao, Chuanliang Feng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laiben GaoState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.ORCID https://orcid.org/0000-0003-0335-4675
Xiaoqiu DouState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.
Chao XingState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.
Kaikai YangState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.
Changli ZhaoState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.
Chuanliang FengState Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200230, P. R. China.ORCID https://orcid.org/0000-0001-6137-5568

Funding

Chinese Postdoctoral Science Foundation 2024M751970Innovation Program of Shanghai Municipal Education Commission 201701070002E00061Interdisciplinary Program of Shanghai Jiao Tong University YG2022QN010National Nature Science Foundation of China 51833006National Nature Science Foundation of China 52373147National Nature Science Foundation of China 52403161National Nature Science Foundation of China 52403193Natural Science Foundation of Shanghai 19ZR1425400Natural Science Foundation of Shanghai 20ZR1425500Postdoctoral Fellowship Program of CPSF GZB20240420)Science and Technology Commission of Shanghai Municipality 20S31904600SJTU Trans-med Awards Research WF5401×62×603
6 · The paper itself

Abstract

Chirality evolution is ubiquitous and important in nature, but achieving it in artificial systems is still challenging. Herein, the chirality evolution of supramolecular helices based on l-phenylalanine derivative (LPF) and naphthylamide derivate (NDIAPY) is achieved by the strategy of electron transfer (ET) assisted secondary nucleation. ET from LPF to NDIAPY can be triggered by 5 s UV irradiation on left-handed LPF-NDIAPY co-assemblies, leading to NDIAPY radical anions and partial disassembly of the helices. Meanwhile, spontaneous reversion of radical anions into monomers occurs upon removal of UV light, and the surface of residual co-assemblies can accelerate the reversion process. This surface accelerated reversion of ET further facilitates the secondary nucleation-elongation events, giving rise to the formation of scale-amplified and g vale-increased left-handed helices. Meanwhile, chirality evolution controlled by ET assisted secondary nucleation process can be also realized by adding the prepared LPF-NDIAPY co-assemblies into the total ET system. This study may provide a useful approach to constructing and modulating diverse chiral structures by manipulating the secondary nucleation process.

Indexed as

chirality evolutionelectron transferhelical nanofiberssecondary nucleationsupramolecular assembly

Identifiers

PMID39679800
PMCPMC11792056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.