Evidence map›Paper›PMID 39679769›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025

Mild-Temperature Catalyzed Hydrosilylation for Simplified Carbohydrate Functionalization of Porous Silicon Nanoparticles.

Maria Grazia Nolli, Monica Terracciano, Ilaria Rea, Stefano D'Errico, Giuseppe Placido Mineo, Luca De Stefano, Gennaro Piccialli, Serena Riela, Giorgia Oliviero, Nicola Borbone

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Modification of Porous Silicon with an Amphiphilic Quaternary Ammonium Hydrocarbon for Nanomedicine Applications.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Grazia NolliDepartment of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy.
Monica TerraccianoDepartment of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy.ORCID https://orcid.org/0000-0001-6367-2419
Ilaria ReaNaples Unit-National Research Council, Institute of Applied Sciences and Intelligent Systems (ISASI), via P. Castellino 111, 80131, Naples, Italy.
Stefano D'ErricoDepartment of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy.
Giuseppe Placido MineoDepartment of Chemical Sciences, University of Catania, Via A. Doria 6, 95125, Catania, Italy.
Luca De StefanoNaples Unit-National Research Council, Institute of Applied Sciences and Intelligent Systems (ISASI), via P. Castellino 111, 80131, Naples, Italy.
Gennaro PiccialliDepartment of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy.
Serena RielaDepartment of Chemical Sciences, University of Catania, Via A. Doria 6, 95125, Catania, Italy.
Giorgia OlivieroISBE-IT, University of Naples Federico II, Corso Umberto I 40, 80138, Naples, Italy.
Nicola BorboneDepartment of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy.

Funding

FRA_2022_MultiHybridAPNRR MUR-M4C2-Investimento 3.1 CUP UNINA: B53C22001800006
6 · The paper itself

Abstract

Porous silicon is one of the most explored nanostructured materials in various biomedical applications owing to its remarkable properties. However, its inherent chemical instability mandates a robust surface modification procedure, and proper surface bioengineering is essential to ensure its effectiveness in the biomedical field. In this study, we introduce a one-pot functionalization strategy that simultaneously stabilizes porous silicon nanoparticles and decorates their surface with carbohydrates through hydrosilylation chemistry, combining mild temperatures and a Lewis acid catalyst. This approach yielded a surface functionalization degree of 300 μmol g

Indexed as

CarbohydratesHydrosilylationNanoparticlesPorous siliconSurface chemical modification

Identifiers

PMID39679769
PMCPMC11724234

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.