Evidence map›Paper›PMID 39679659›Full record

ArticleeLife2024

Microstructural asymmetries of the planum temporale predict functional lateralization of auditory-language processing.

Peipei Qin, Qiuhui Bi, Zeya Guo, Liyuan Yang, Haokun Li, Peng Li, Xinyu Liang, Junhao Luo, Xiangyu Kong, Yirong Xiong and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peipei Qin *State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Qiuhui Bi *School of Artificial Intelligence, Beijing Normal University, Beijing, China.
Zeya GuoState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Liyuan YangState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Haokun LiState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Peng LiState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Xinyu LiangState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Junhao LuoState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.ORCID https://orcid.org/0000-0002-3207-1597
Xiangyu KongState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Yirong XiongState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Bo SunSchool of Artificial Intelligence, Beijing Normal University, Beijing, China.
Sebastian OcklenburgDepartment of Psychology, Medical School Hamburg, Hamburg, Germany.
Gaolang GongState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.ORCID https://orcid.org/0000-0001-5788-022X

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Fundamental Research Funds for the Central Universities 2233200020National Natural Science Foundation of China 82021004National Natural Science Foundation of China 82172016National Natural Science Foundation of China T2325006NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Structural hemispheric asymmetry has long been assumed to guide functional lateralization of the human brain, but empirical evidence for this compelling hypothesis remains scarce. Recently, it has been suggested that microstructural asymmetries may be more relevant to functional lateralization than macrostructural asymmetries. To investigate the link between microstructure and function, we analyzed multimodal MRI data in 907 right-handed participants. We quantified structural asymmetry and functional lateralization of the planum temporale (PT), a cortical area crucial for auditory-language processing. We found associations between PT functional lateralization and several structural asymmetries, such as surface area, intracortical myelin content, neurite density, and neurite orientation dispersion. The PT structure also showed hemispheric-specific coupling with its functional activity. All these functional-structural associations are highly specific to within-PT functional activity during auditory-language processing. These results suggest that structural asymmetry underlies functional lateralization of the same brain area and highlights a critical role of microstructural PT asymmetries in auditory-language processing.

Indexed as

Functional LateralityMagnetic Resonance ImagingAdultAuditory PerceptionBrain MappingFemaleHumansLanguageMaleTemporal LobeYoung Adultbrain asymmetryfunctional lateralizationheschl's gyrushumanlanguage processingneuroscienceplanum temporale

Identifiers

PMID39679659
PMCPMC11649236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.