Evidence map›Paper›PMID 39679617›Full record

ArticleGut microbes

Supplier-origin gut microbiomes affect host body weight and select autism-related behaviors.

Zachary L McAdams, Kevin L Gustafson, Amber L Russell, Rachel Self, Amy L Petry, Teresa E Lever, Aaron C Ericsson

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zachary L McAdamsMolecular Pathogenesis & Therapeutics Program, University of Missouri, Columbia, MO, USA.ORCID 0000-0003-2883-507X
Kevin L GustafsonMU Metagenomics Center, University of Missouri, Columbia, MO, USA.ORCID 0000-0002-2104-8762
Amber L RussellDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO, USA.ORCID 0000-0003-1291-5374
Rachel SelfDivision of Animal Sciences, University of Missouri, Columbia, MO, USA.
Amy L PetryDivision of Animal Sciences, University of Missouri, Columbia, MO, USA.ORCID 0000-0003-2145-2199
Teresa E LeverDepartment of Otolaryngology, School of Medicine, University of Missouri, Columbia, MO, USA.ORCID 0000-0002-5587-3816
Aaron C EricssonMolecular Pathogenesis & Therapeutics Program, University of Missouri, Columbia, MO, USA.ORCID 0000-0002-3053-7269

Funding

The Mutant Mouse Resource and Research Center at the University of Missouri - ResourceU42OD010918 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI Bret Daniel Ulery · 2012 to 2026
$25.1M
MOLECULAR BASIS OF GENE EXPRESSION AND SIGNAL PROCESSINGT32GM008396 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI HANNINK, MARK · 1991 to 2021
$4.1M
Postdoctoral Training in Comparative MedicineT32OD011126 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI Elizabeth C Bryda, Aaron Ericsson · 2012 to 2026
$3.4M
NIGMS NIH HHS T32 GM008396NIH HHS T32 OD011126NIH HHS U42 OD010918
6 · The paper itself

Abstract

Autism spectrum disorders (ASD) are complex human neurodiversities increasing in prevalence within the human population. In search of therapeutics to improve quality-of-life for ASD patients, the gut microbiome (GM) has become a promising target as a growing body of work supports roles for the complex community of microorganisms in influencing host behavior via the gut-brain-axis. However, whether naturally-occurring microbial diversity within the host GM affects these behaviors is often overlooked. Here, we applied a model of population-level differences in the GM to a classic ASD model - the BTBR T

Indexed as

Autism Spectrum DisorderBehavior, AnimalBody WeightGastrointestinal MicrobiomeAnimalsAutistic DisorderBacteriaBrain-Gut AxisDisease Models, AnimalFemaleHumansMaleMiceASDBTBREnvigogrowthgut-brain-axismicrobiomesupplier-origin GMThe Jackson Laboratory

Identifiers

PMID39679617
PMCPMC11305029

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.