Evidence map›Paper›PMID 39679397›Full record

ArticleBiomedical optics express2024

Absolute depth-resolved optic axis measurement with catheter-based polarization sensitive optical coherence tomography.

Shadi Masoumi, Jaeyul Lee, Georgia L Jones, Mireille Quémener, Martin Parent, Brett E Bouma, Lida P Hariri, Daniel C Côté, Martin Villiger

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shadi MasoumiCERVO Brain Research Center, Université Laval, Québec, Québec, Canada.ORCID https://orcid.org/0000-0001-6952-1582
Jaeyul LeeHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-9207-7026
Georgia L JonesHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-1657-5912
Mireille QuémenerCERVO Brain Research Center, Université Laval, Québec, Québec, Canada.
Martin ParentCERVO Brain Research Center, Université Laval, Québec, Québec, Canada.
Brett E BoumaHarvard Medical School, Boston, MA, USA.
Lida P HaririHarvard Medical School, Boston, MA, USA.
Daniel C CôtéCERVO Brain Research Center, Université Laval, Québec, Québec, Canada.
Martin VilligerHarvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0003-3819-1271

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
In vivo endobronchial OCT for IPF diagnosis and therapy response assessmentR01HL152075 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HARIRI, LIDA P · 2020 to 2024
$4.0M
Universal optical coherence polarimetryR01EB033321 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI VILLIGER, MARTIN · 2022 to 2025
$2.0M
NHLBI NIH HHS R01 HL152075NIBIB NIH HHS P41 EB015903NIBIB NIH HHS R01 EB033321
6 · The paper itself

Abstract

Imaging depth-resolved birefringence and optic axis orientation with polarization sensitive optical coherence tomography (PS-OCT) unveils details of tissue structure and organization that can be of high pathophysiologic, mechanistic, and diagnostic value. For catheter-based PS-OCT, the dynamic rotation of the fiber optic probe, in addition to the polarization effects of the system components, complicates the reliable and robust reconstruction of the sample's optic axis orientation. Addressing this issue, we present a new method for the reconstruction of absolute depth-resolved optic axis orientation in catheter-based PS-OCT by using the intrinsic retardance of the protecting catheter sheath as a stable guide star signal. Throughout the paper, we rigorously inspect the retardance and optic axis orientation of the sheath and validate our method by imaging a birefringent phantom with known optic axis orientation. Reconstructing the optic axis orientation of the phantom, placed at different locations around the catheter, we measured an average absolute deviation (AAD) for the mean optic axis orientation over cross-sectional images of 3.28°, even with significant bending stress on the catheter. This corresponds to an almost three-fold improvement compared to our earlier method (optic axis AAD of 9.41°). We finally highlight the capability of our reconstruction with stereotactic catheter-based PS-OCT of a fresh sheep brain.

Identifiers

PMID39679397
PMCPMC11640563

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.