ArticleBiomedical optics express2024
Quantitative investigations on light emission profiles for interstitial laser treatment.
Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Non-ablative transurethral laser treatment for collagen remodeling with functional recovery in an in vivo model of stress urinary incontinence.Scientific reports · 2026Article
- Next-Generation Cancer Treatment: Photoimmunotherapy's Promise for Unresectable Head and Neck Cancers.Pharmaceutics · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interstitial laser treatment (ILT) using a diffusing applicator (DA) has been employed to treat tumors. However, the treatment efficacy and safety of the emission profiles from DAs have been poorly explored. This study investigated the effect of the emission profiles from DAs on prostate tumor treatment. Dual-peak and proximal-/distal-end peak profiles using 980 nm laser at 5 W for 60 s were tested to compare the extent of thermal coagulation in soft tissue numerically and experimentally. The numerical simulation predicted the temperature development in the tissue. Ex vivo porcine liver and in vivo rat models were used to compare the performance of the profiles. The dual-peak profile yielded a coagulation extent that was almost equivalent to that of the flat-top profile (in simulation) and 1.3 times larger than those of the other profiles in both ex vivo and in vivo. The dual-peak profile predictably entailed uniform coagulation within the irradiated region. Further in vivo studies using different tumor sizes will be evaluated to warrant the efficacy and safety of the dual-peak profile for the ILT of prostate tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.