Evidence map›Paper›PMID 39679356›Full record

ArticleOpen forum infectious diseases2024

Development of a City-wide Rapid Antiretroviral Therapy Initiation Toolkit for People Newly Diagnosed With HIV in the Southern United States.

A C Pettit, A A Ahonkhai, L Pierce, P F Rebeiro, C M Valdebenito, J Woods, L Gregory, C Walton, R Nash, N A Summers and 6 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

A C PettitDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0001-8832-0866
A A AhonkhaiDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
L PierceDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
P F RebeiroDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-1951-9104
C M ValdebenitoUniversity of Memphis School of Public Health, Division of Social and Behavioral Sciences, Memphis, Tennessee, USA.
J WoodsAngelic Branding Consulting, Nashville, Tennessee, USA.
L GregoryTennessee Department of Health, Nashville, Tennessee, USA.ORCID https://orcid.org/0009-0000-6027-9304
C WaltonTennessee Department of Health, Nashville, Tennessee, USA.
R NashTennessee Department of Health, Nashville, Tennessee, USA.
N A SummersDepartment of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0002-1979-9313
A Van WylenChrist Community Health Services, Memphis, Tennessee, USA.
D ThompsonChrist Community Health Services, Memphis, Tennessee, USA.
M Hayes-WintonShelby County Health Department, Memphis, Tennessee, USA.
A EkeDivision of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-3649-7552
L C PichonUniversity of Memphis School of Public Health, Division of Social and Behavioral Sciences, Memphis, Tennessee, USA.
C M AudetDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2015 to 2026
$27.5M
Implementation of Rapid HIV Testing and Linkage to HIV Treatment or Prevention Among Vulnerable Populations in TennesseeU01PS005240 · PS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUDET, CAROLYN, PETTIT, APRIL · 2021 to 2025
$5.9M
NCHHSTP CDC HHS U01 PS005240NIAID NIH HHS P30 AI110527
6 · The paper itself

Abstract

Background: Rapid antiretroviral therapy (ART) initiation, in which individuals with HIV start treatment within days of diagnosis, is a key component of the United States (US) Ending the HIV Epidemic initiative. The Memphis Metropolitan Statistical Area ranks second in the US for HIV incidence, yet only ∼60% of individuals link to treatment within 1 month of diagnosis. This study aimed to identify barriers and strategies for implementing rapid ART initiation in Memphis. Methods: From August to December 2022, we conducted process mapping guided by the Consolidated Framework for Implementation Research to outline the steps from 3 HIV testing sites to ART prescription at 3 Ryan White-funded clinics in Memphis, Tennessee. We used modified conjoint analyses to prioritize barriers and identify strategies for improving rapid ART implementation, focusing on the importance and feasibility of changes. Findings: Prioritized barriers included intersectional stigma and a lack of access to centralized information about the rapid ART program, branding and logo development, inter- and intra-organizational networking and communication, testing and treatment resources (HIV testing kits and ART starter packs), rapid ART knowledge, and organizational champions. Strategies to address these barriers were compiled into a local rapid ART toolkit. Conclusions: We identified modifiable systemic barriers to rapid ART initiation in Memphis, a community disproportionately affected by HIV. The strategies developed to address these barriers informed the creation of a locally relevant rapid ART toolkit for future evaluation. These methods could be applied in other high-burden areas seeking to develop local rapid ART models.

Identifiers

PMID39679356
PMCPMC11643345

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.