ArticleTherapeutic advances in infectious disease
Prognostic performance of the Age, PaO
Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: A predictive scoring system used in patients with acute respiratory distress syndrome (ARDS) known as Age, PaO Objective: To assess the association between APPS and mortality, as well as APPS performance in predicting mortality within 28 days of intensive care unit (ICU) admission in patients with ARDS due to COVID-19. Design: Analytical observational retrospective cohort study. Methods: We conducted a retrospective cohort study in patients diagnosed with ARDS according to the Berlin criteria who were admitted to the ICU. We evaluated the prognostic performance of APPS using the area under the receiver operating characteristic curve (AUC-ROC), and association with mortality was measured using the Cox proportional hazards regression models. Results: A total of 271 patients were analyzed. The AUC for 28-day mortality was 0.78 (95% CI: 0.73-0.84). In the Cox proportional hazards model, after adjusting for sex and categorized Charlson Comorbidity Index, it was found that grade 2 APPS (aHR: 3.67, 95% CI: 2.14-6.30, Conclusion: The APPS scoring system has a good prognostic performance for mortality in patients diagnosed with COVID-19-induced ARDS.
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