ArticleJournal of thoracic disease2024
Development and validation of a nomogram for incorporating
Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development of a predictive model for lymph node metastasis in esophageal cancer usingJournal of gastrointestinal oncology · 2025Article
- Development and validation of a nomogram for predicting long-term survival in pN + esophageal squamous cell carcinoma treated using radical resection without neoadjuvant therapy.Annals of medicine · 2025Article
- Article
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Authors and funding
10 authors.
Funding
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Abstract
Background: There is currently no widely accepted prognostic model specifically for elderly patients with esophageal squamous cell carcinoma (ESCC) undergoing radiotherapy. This study aimed to develop a nomogram incorporating metabolic imaging parameters from Methods: A retrospective analysis was conducted on 118 elderly patients with ESCC treated with radiotherapy. The patients were evaluated using Results: SLR and Lv were found to be independent predictors of OS in elderly patients with ESCC. The nomogram developed by incorporating these factors, along with cTNM staging, showed superior predictive power compared to the traditional TNM staging system. ROC curve analysis demonstrated greater accuracy in predicting 1-, 2-, and 3-year OS rates, with area under the curve (AUC) values of 0.771, 0.763, and 0.815, respectively. DCA confirmed that the nomogram provided a greater clinical benefit. Patients were stratified into low-risk, intermediate-risk, and high-risk groups, with corresponding 3-year OS rates of 60.3%, 25.0%, and 3.6%, respectively. Conclusions: The developed nomogram incorporating SLR, Lv, and cTNM staging offers a reliable tool for the risk stratification of elderly patients with ESCC undergoing radiotherapy. This model may serve as a reference for personalized treatment planning, potentially improving clinical outcomes in this patient population.
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