Evidence map›Paper›PMID 39678845›Full record

ArticleJournal of thoracic disease2024

Uniportal video-assisted thoracoscopic thymectomy in Hospital Kuala Lumpur: a retrospective observational review of outcomes for patients diagnosed with thymomatous and non-thymomatous myasthenia gravis.

Dinesh Francis K Balasingam, Benedict Dharmaraj, Diong Nguk Chai, Narendran Balasubbiah, Palaniappan Meiyappan, Narasimman Sathiamurthy

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dinesh Francis K BalasingamDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0009-0003-1866-2272
Benedict DharmarajDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-6767-8022
Diong Nguk ChaiDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-3584-4073
Narendran BalasubbiahDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-9938-7721
Palaniappan MeiyappanDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-9814-2565
Narasimman SathiamurthyDivision of Thoracic Surgery, Department of General Surgery, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0003-3129-4606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The standard treatment for thymomatous myasthenia gravis (TMG) patients is thymectomy, whereas its role in non-TMG (NTMG) is still under debate. The objective of this study is to assess myasthenia gravis (MG) outcomes of thymectomy using the uniportal video-assisted thoracoscopic surgery (UVATS) technique for both groups and evaluate the procedure's efficacy and safety. Methods: We retrospectively collected data from January 2019 to December 2022 at Hospital Kuala Lumpur. The Myasthenia Gravis Activities of Daily Living (MG-ADL) scoring and the Myasthenia Gravis Foundation of America's Post Interventional Score (MGFA-PIS) measured our primary outcome. Secondary outcomes included surgery-related morbidity. All patients underwent a UVATS thymectomy, with the incision at the right anterior axillary line at the 5 Results: Out of 26 patients, 22 were analysed. The MG-ADL scores indicated a significant mean score reduction post-surgery [6.9; 95% confidence interval (CI): 4.42 to 9.67; P<0.001]. NTMG patients exhibited a greater decrease in MG-ADL mean score than TMG patients {9.5 [standard deviation (SD) 4.8] Conclusions: Thymectomy via UVATS is an effective and safe approach for improving symptoms in both TMG and NTMG patients.

Indexed as

minimally invasivemyasthenia gravis (MG)thymectomyuniportalVideo-assisted thoracoscopic surgery (VATS)

Identifiers

PMID39678845
PMCPMC11635260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.