ReviewAmerican journal of translational research2024
Comparison of the anesthetic effect of sufentanil versus fentanyl in pediatric surgical patients: a meta-analysis.
Review in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
objectiveTo evaluate the anesthetic effects of sufentanil and fentanyl in pediatric surgery.
methodsWe conducted a comprehensive search across multiple databases, including Wanfang, CNKI, Chinese Biomedical Literature, VIP, Embase, PubMed, Cochrane Library, and Web of Science. Studies were retrieved to screen randomized controlled trials (RCTs) comparing sufentanil and fentanyl use in children during surgery. Primary outcomes included mean arterial pressure (MAP), heart rate (HR), Ramsay sedation score, and restlessness score (RS). Pooled and sensitivity analyses were performed, and risk of bias was assessed.
resultsFourteen studies compared the efficacy of sufentanil and fentanyl in terms of MAP immediately after intubation. The results demonstrated that sufentanil exhibited a more pronounced reduction in MAP compared with fentanyl (SMD: -0.62; 95% CI = [-0.97, -0.27]; I
conclusionAmong the children undergoing surgery, sufentanil demonstrates more advantages over fentanyl in maintaining stable hemodynamics and reducing postoperative agitation, offering better clinical benefits.
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