Evidence map›Paper›PMID 39678493›Full record

ArticleFrontiers in oncology2024

A correlation study between cervical cancer and sex hormones.

Xian Wu, Yitao You, Zhichong Guan, Yongpiao Ban, Yiping Wang, Dianhua Du, Bo Wang, Wen Wu, Yue Wen, Yixian Ren and 3 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xian WuHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yitao YouHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Zhichong GuanSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Yongpiao BanHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yiping WangHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Dianhua DuHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Bo WangHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Wen WuHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yue WenInstitute of Environmental and School Hygiene and Disinfection, Sichuan Center For Disease Control and Prevention, Chengdu, China.
Yixian RenKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Chunwei WuHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Xuelin ZhangHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Lan MoHealth Management Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aims of this study were to investigate the association between positive TCT and sex hormone levels and to evaluate the feasibility of change in sex hormone level as a potential predictor of cervical cancer. Methods: We recruited 910 female participants from the health examination center of a hospital in Guizhou between 2019 and 2023. All participants had undergone both hematologic examinations and cervical cancer screening. Results: A total of 265 participants had positive TCT screening. Luteinizing hormone, estradiol, prolactin, and progesterone were negatively correlated with positive TCT screening. Age, systolic blood pressure, alanine aminotransferase, aspartate aminotransferase, urea, fasting blood glucose, low-density lipoprotein, total cholesterol, triglyceride, erythrocyte, follicle-stimulating hormone, and testosterone were positively correlated with positive TCT screening. Logistic regression analysis showed that prolactin, red blood cell count, and age were risk factors for cervical cancer, while FSH was a protective factor for cervical cancer. The AUC of FSH and age in the prediction model was 0.701 and 0.705, respectively. Conclusion: The incidence of cervical cancer increases with increased age and follicle poietin level. At the same time, the increase in FSH level has a certain predictive value for the incidence of cervical cancer.

Indexed as

cervical cancerfollicle-stimulating hormoneprolactinsex hormonesthin prep cytologic test

Identifiers

PMID39678493
PMCPMC11638056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.